{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:55:02Z","timestamp":1753869302005,"version":"3.41.2"},"reference-count":50,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Epidemiological data on seasonal coronaviruses (sCoVs) may provide insight on transmission patterns and demographic factors that favor coronaviruses (CoVs) with greater disease severity. This study describes the incidence of CoVs in several high\u2010risk groups in Ottawa, Canada, from October 2020 to March 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Serological assays quantified IgG and IgM antibodies to SARS\u2010CoV\u20102, HCoV\u2010OC43, HCoV\u2010NL63, HCoV\u2010HKU1, and HCoV\u2010229E. Incident infections were compared between four population groups: individuals exposed to children, transit users, immunocompromised, and controls. Associations between antibody prevalence indicative of natural infection and demographic variables were assessed using regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Transit users and those exposed to children were at no greater risk of infection compared to the control group. Fewer infections were detected in the immunocompromised group (<jats:italic>p<\/jats:italic>\u2009=\u2009.03). SARS\u2010CoV\u20102 seroprevalence was greater in individuals with low income and within ethnic minorities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our findings suggest that nonpharmaceutical interventions intended to reduce SAR\u2010CoV\u20102 transmission protected populations at high risk of exposure. The re\u2010emergence of sCoVs and other common respiratory viruses alongside SARS\u2010CoV\u20102 may alter infection patterns and increase the risk in vulnerable populations.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iid3.1342","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T14:01:01Z","timestamp":1721311261000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reduced seasonal coronavirus incidence in high\u2010risk population groups during the COVID\u201019 pandemic"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1988-1034","authenticated-orcid":false,"given":"Aliisa","family":"Heiskanen","sequence":"first","affiliation":[{"name":"School of Epidemiology and Public Health, Faculty of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yannick","family":"Galipeau","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Microbiology &amp; Immunology, Faculty of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julian","family":"Little","sequence":"additional","affiliation":[{"name":"School of Epidemiology and Public Health, Faculty of Medicine University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc\u2010Andr\u00e9","family":"Langlois","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Microbiology &amp; Immunology, Faculty of Medicine University of Ottawa Ottawa Ontario Canada"},{"name":"Centre for Infection, Immunity and Inflammation (CI3) University of Ottawa Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Curtis L.","family":"Cooper","sequence":"additional","affiliation":[{"name":"School of Epidemiology and Public Health, Faculty of Medicine University of Ottawa Ottawa Ontario Canada"},{"name":"Ottawa Hospital Research Institute Ottawa Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"World Health Organization. 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