{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:53:38Z","timestamp":1740171218352,"version":"3.37.3"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T00:00:00Z","timestamp":1568764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the clinical and allergic features of uncontrolled allergic rhinitis (UCAR) in the Democratic Republic of Congo (DRC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Observational cross\u2010sectional study of 311 patients with UCAR. Allergic rhinitis was diagnosed clinically with sensitization to inhalant allergens and then confirmed by skin prick test. Severity was assessed using the Visual Analog Scale (VAS), with VAS scores greater than or equal to 5 used as cut off to determine uncontrolled status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of UCAR patients was 30.7\u2009\u00b1\u200915.1 years and 66.9% of the patients were females. Three out of four patients had persistent UCAR while the remainder had intermittent symptoms. UCAR was associated with rhinosinusitis and asthma in 18.6% and 18% of the patients, respectively. Among UCAR patients, 95.2% were polysensitized. The allergens most frequently involved were mites (82%), cat (27.3%), and dog (26.7%). The most frequent symptoms were nasal congestion, sneezing, and runny nose. There were 44.4% of the patients treated with nasal corticosteroids and 33.1% with oral antihistamine (anti\u2010H1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study reports on the clinical phenotype of UCAR in the DRC. The findings contribute to our understanding of UCAR in this population and may be used to implement strategies to reduce the prevalence and burden of UCAR in this setting.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iid3.272","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T09:34:48Z","timestamp":1568799288000},"page":"286-291","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0992-4707","authenticated-orcid":false,"given":"Patricia K.","family":"Kakobo","sequence":"first","affiliation":[{"name":"ENT Service Kinshasa University Hospital  Kinshasa Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilaire K.","family":"Kalala","sequence":"additional","affiliation":[{"name":"ENT Service Kinshasa University Hospital  Kinshasa Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maguy M.","family":"Tshibola","sequence":"additional","affiliation":[{"name":"ENT Service Kinshasa University Hospital  Kinshasa Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph K.","family":"Kelekele","sequence":"additional","affiliation":[{"name":"Ophtalmology Service Kinshasa University Hospital  Kinshasa Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieudonn\u00e9 T.","family":"Nyembue","sequence":"additional","affiliation":[{"name":"ENT Service Kinshasa University Hospital  Kinshasa Democratic Republic of Congo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter W.","family":"Hellings","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology and Head and Nose Surgery University Hospital of Leuven  Leuven Belgium"},{"name":"Department of Otorhinolaryngology, Academic Medical Center University of Amsterdam  Amsterdam The Netherlands"},{"name":"Upper Airways Research Laboratory University of Ghent  Ghent Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"e_1_2_8_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01620.x"},{"key":"e_1_2_8_1_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/2045-7022-1-2"},{"key":"e_1_2_8_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.06.034"},{"key":"e_1_2_8_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aller.2012.03.001"},{"key":"e_1_2_8_1_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03891.x"},{"key":"e_1_2_8_1_7_1","doi-asserted-by":"publisher","DOI":"10.26719\/2009.15.1.167"},{"key":"e_1_2_8_1_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000068377"},{"key":"e_1_2_8_1_9_1","doi-asserted-by":"publisher","DOI":"10.2500\/ar.2012.3.0023"},{"key":"e_1_2_8_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60130-X"},{"key":"e_1_2_8_1_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12040"},{"key":"e_1_2_8_1_12_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4079"},{"key":"e_1_2_8_1_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12948-018-0082-y"},{"key":"e_1_2_8_1_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01549.x"},{"key":"e_1_2_8_1_15_1","first-page":"27","article-title":"Survey of the burden of allergic rhinitis in Spain","volume":"19","author":"Mullol JA","year":"2009","journal-title":"J Invest Allergol Clin Immunol"},{"key":"e_1_2_8_1_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.07.053"},{"key":"e_1_2_8_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.01276.x"},{"key":"e_1_2_8_1_18_1","first-page":"543","article-title":"Practice parameters for allergy diagnostic testing. 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