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Specific food allergens including cow's milk protein, are partially causative to disease progression, and dietary management forms three main options; the elemental diet (ED), the empirical elimination diet (EED), and the targeted elimination diet (TED). The dietary choice should be individualized, however, the European Society for Pediatric Gastroenterology, Hepatology and Nutrition guidelines recommend an ED for pediatric EoE with multiple food allergies, failure to thrive, unresponsive disease or unable to follow a highly restricted diet. The aim of this narrative review was to explore the effectiveness of the ED (using amino acid formula [AAF]), in the management of pediatric EoE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Literature searches were performed to identify eligible studies that described outcomes including eosinophil count, clinical symptoms, growth, and medications.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, 10 eligible studies were found, with n\u2009=\u2009462 patients assigned to receive AAF from a total of n\u2009=\u2009748 (average age 6.7 years), for a duration of 4 to 8 weeks. The use of AAF reduced eosinophil levels and demonstrated remission (defined as \u226410 eosinophils per high power field) in 75%\u2010100% of children with improvements, if not resolution, in clinical symptoms. AAF was more clinically effective than the use of the EED or TED, where remission rates were 75%\u201081% and 40%\u201069%, respectively. Few studies collected growth outcomes, however where documented these were positive for those on AAF. The long\u2010term impacts of each diet were not thoroughly explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of AAF is a clinically effective management option for pediatric EoE, and further research is required to guide long\u2010term management.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iid3.273","type":"journal-article","created":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T12:20:03Z","timestamp":1573042803000},"page":"292-303","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["The use of amino acid\u2010based nutritional feeds is effective in the dietary management of pediatric eosinophilic oesophagitis"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2265-7321","authenticated-orcid":false,"given":"Kiranjit","family":"Atwal","sequence":"first","affiliation":[{"name":"Medical Affairs Nutricia Ltd  Trowbridge United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary P.","family":"Hubbard","sequence":"additional","affiliation":[{"name":"Medical Affairs Nutricia Ltd  Trowbridge United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carina","family":"Venter","sequence":"additional","affiliation":[{"name":"Section of Allergy and Immunology, Children's Hospital Colorado University of Colorado Denver School of Medicine  Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca J.","family":"Stratton","sequence":"additional","affiliation":[{"name":"Medical Affairs Nutricia Ltd  Trowbridge United Kingdom"},{"name":"Faculty of Medicine University of Southampton  Southampton United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,11,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.02.040"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3182a80be1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181788282"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.71"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j4482"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.08.017"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2010.03.018"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2014.09.007"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12846"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/2050640616689525"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12429"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318291fee2"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15231"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2018.06.028"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.07.016"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474124.2017.1271324"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002215"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.08.038"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgh3.12059"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.01.030"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.02.006"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.giec.2007.09.008"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2015.06.013"},{"key":"e_1_2_7_25_1","unstructured":"PubMed.http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi. 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