{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T10:34:07Z","timestamp":1783766047489,"version":"3.55.0"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T00:00:00Z","timestamp":1592352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose is a comparative study of the cellular reactions in capillary and venous blood in northerners under general hypothermia in a climatic chamber during different photoperiods. The authors examined 108 relatively healthy people (80 women and 28 men aged 21\u2010 to 50\u2010years old).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study included determining the hemogram, neutrograms, monocytograms, lymphocytograms, and phagocytic activity neutrophil granulocytes, enzyme immunoassay, flow cytometry, indirect immunoperoxidase, bioluminescence, systolic and diastolic blood pressure, and body temperature in the ear canal and on the skin of the rear left side of the right hand of volunteers before the effect of general cooling in the room at an air temperature and after 5\u2009minutes of exposure to cold air.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>It was established that total neutrophil count in venous blood was lower by 8.07%\u2009\u00b1\u20090.41%, monocyte count by 51.32%\u2009\u00b1\u20091.03%, and basophil count by 50.21%\u2009\u00b1\u20091.24% than in capillary blood, but the lymphocyte count was higher by 25.23%\u2009\u00b1\u20090.41% due to smaller forms that are known to be recirculating. After a 5\u2010minute period in a climatic chamber at \u221225\u00b0C in 27.53% of individuals during a polar night and in 16.51% volunteers during a polar day had elevated levels of neutrophils in the venous blood due to the increase in the levels of tumor necrosis factor\u2010\u03b1 in blood and decrease in noradrenaline, adrenaline, and irisin.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The systematic effect of general cooling, especially during the polar night, leads to a reduction in reserve adaptability with the formation of neutropenia, deficiency of phagocytic defense, and functional insufficiency of T\u2010lymphocytes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iid3.322","type":"journal-article","created":{"date-parts":[[2020,6,18]],"date-time":"2020-06-18T05:28:27Z","timestamp":1592458107000},"page":"408-414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cellular reactions in capillary and venous blood in northerners to a short\u2010term period in a climatic chamber"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5080-6502","authenticated-orcid":false,"given":"Liliya K.","family":"Dobrodeeva","sequence":"first","affiliation":[{"name":"N. 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