{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T06:03:05Z","timestamp":1776232985628,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>House dust mite allergy affects 65\u2013130 million people worldwide. Untreated patients could develop severe allergic diseases such as atopic dermatitis and asthma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We consecutively recruited 50 patients with a clinical diagnosis of allergic rhinitis\/rhino conjunctivitis. Mite Skin Prick Tests were performed. Mite specific IgE were tested.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Ninety\u2010six per cent of the patients had a positive prick test for Dpt, Dfar 94%, Ldt 86%, Tput 82%, and Blot 82%. Der p1 was recognized by 70%, Der p2 84%, Der p23 72%. Regarding serodominances, Der p2 was the highest one (30.2\u2009kU\/L). Forty\u2010three patients presented sensitization to 3\n                      <jats:italic>Dermatophagoides pteronyssinus<\/jats:italic>\n                      molecules, been 1\u2009+\u20092\u2009+\u200923 the main combination. Der p 1, 2, and 23 prevalence were similar in patients with intermittent or persistent allergic rhinitis. All patients with asthma recognized to Der p2 and more than 80% Der p1 and 23. In the group of patients without asthma, sensitivity to Der p23 is considerably reduced.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Ninety per cent of patients recognize Der p1, 2, and 23, alone or in any of their combinations. The high prevalence of sensitization to Der p23 (72%) stands out, that all asthmatic patients are sensitive to Der p2 and that sensitization to Der p23 in non\u2010asthmatic patients drops to 50%.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iid3.70254","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:27:05Z","timestamp":1760556425000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dust Mite Serodominance Profiles in Lugo"],"prefix":"10.1002","volume":"13","author":[{"given":"Francisco","family":"Carballada","sequence":"first","affiliation":[{"name":"Secci\u00f3n de Alergia del Hospital Universitario Lucus Augusti de Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Alfredo","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Alergia del Hospital Universitario Lucus Augusti de Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram\u00f3n","family":"N\u00fa\u00f1ez","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Alergia del Hospital Universitario Lucus Augusti de Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Lopez","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Alergia del Hospital Universitario Lucus Augusti de Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joaqu\u00edn","family":"Mart\u00edn","sequence":"additional","affiliation":[{"name":"Secci\u00f3n de Alergia del Hospital Universitario Lucus Augusti de Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Giangrande","sequence":"additional","affiliation":[{"name":"Hospital da Costa Burela Lugo Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Garc\u00eda\u2010Dumpierrez","sequence":"additional","affiliation":[{"name":"Hospital Universitario Dr. Negr\u00edn Gran Canaria Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6092-8839","authenticated-orcid":false,"given":"Javier","family":"Alcover","sequence":"additional","affiliation":[{"name":"Laboratorios DIATER Legan\u00e9s Madrid Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Laboratorios DIATER Legan\u00e9s Madrid Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Palacios","sequence":"additional","affiliation":[{"name":"Laboratorios DIATER Legan\u00e9s Madrid Espa\u00f1a"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,10,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2023.04.008"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.15304\/rr.id5318"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1159\/000523869"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12796"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0439"},{"issue":"3","key":"e_1_2_11_7_1","first-page":"169","article-title":"House Dust Mite Species and Allergen Levels in Galicia, Spain: A Cross\u2010Sectional, Multicenter, Comparative Study","volume":"16","author":"\u2010Boquete M.","year":"2006","journal-title":"Journal of Investigational Allergology & Clinical Immunology"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.18176\/jiaci.0533"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.10.012"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2007.01620.x"},{"key":"e_1_2_11_11_1","unstructured":"\u201cGlobal Initiative for Asthma Global Strategy for Asthma Management and Prevention \u201d accessed August 18 2021 www.ginasthma.org."},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.23822\/EurAnnACI.1764-1489.195"},{"issue":"6","key":"e_1_2_11_14_1","first-page":"648","article-title":"Mite Component\u2010Specific IgE Repertoire and Phenotypes of Allergic Disease in Childhood: The Tropical Perspective [Published Correction Appears in","volume":"22","author":"Kidon M. 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