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Since its emergence in 2019, more than 7 million deaths have been reported worldwide. Vaccines have been the most effective strategy for preventing severe illness and death in patients who acquire the infection. Vaccines induce both humoral and cell\u2010mediated immune responses; the latter is crucial in the immune response against SARS\u2010CoV\u20102, as the effector mechanisms of T\u2010cells are less affected by the high mutation rate of the virus and prevail through memory phenotypes, ensuring long\u2010term protection. mRNA vaccines have been primarily used worldwide to control the COVID\u201019 pandemic. This platform can protect against different circulating variants and is characterized by generating a robust T\u2010cell response. This review discusses the immune response of T\u2010cells induced by mRNA vaccines against SARS\u2010CoV\u20102. 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