{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T05:59:10Z","timestamp":1776146350043,"version":"3.50.1"},"reference-count":49,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients with autoimmune disorders are highly susceptible to infections including cytomegalovirus (CMV) leading to serious complications ranging from asymptomatic to severe systemic diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>The first case was a 44\u2010year\u2010old woman with systemic lupus erythematosus (SLE) referred to the Rheumatology ward due to a necrotizing ulcer on the hand's finger and multiple ulcerative lesions on her lips and tongue. She had pancytopenia and tested positive for both herpes simplex virus (HSV) and CMV polymerase chain reaction (CMV\u2010PCR). She was treated with ganciclovir for 14 days and subsequently recovered. The second case was a 55\u2010year\u2010old man, a known sarcoidosis case, admitted to the hospital due to lower extremities weakness and intraoral ulcers. The lab findings revealed leukopenia and elevated levels of ESR and CRP. Viral markers were all negative except for the CMV\u2010PCR test. Electromyography and nerve conduction velocity (EMG\u2010NCV) showed subacute axonal motor polyneuropathy in the lower limbs. Due to the high titers of CMV (500,000\u2009copies\/mL), he was treated with ganciclovir for 2 weeks and the symptoms improved dramatically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CMV infection in patients with inflammatory rheumatic diseases may lead to rare manifestations that can be misdiagnosed as a flare of the underlying disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iid3.70377","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T10:00:25Z","timestamp":1773828025000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytomegalovirus Infection Mimics Manifestations of Underlying Diseases in Patients With Autoimmune Disorders: A Case Report and Literature Review"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7273-544X","authenticated-orcid":false,"given":"Elaheh","family":"Karimi","sequence":"first","affiliation":[{"name":"School of Medicine Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8798-3278","authenticated-orcid":false,"given":"Zahra","family":"Moradi","sequence":"additional","affiliation":[{"name":"School of Medicine Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3123-1149","authenticated-orcid":false,"given":"Somayeh","family":"Soroureddin","sequence":"additional","affiliation":[{"name":"Rheumatology Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5613-2868","authenticated-orcid":false,"given":"Ozra","family":"Nouri","sequence":"additional","affiliation":[{"name":"Rheumatology Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8718-8784","authenticated-orcid":false,"given":"Zahra","family":"Tamartash","sequence":"additional","affiliation":[{"name":"Rheumatology Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4762-6943","authenticated-orcid":false,"given":"Hoda","family":"Kavosi","sequence":"additional","affiliation":[{"name":"Rheumatology Research Center Tehran University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781003193616-4"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/pqa98i"},{"key":"e_1_2_14_4_1","volume-title":"Open Forum Infectious Diseases","author":"Bruminhent J.","year":"2021"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221793"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.174490"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-019-04324-6"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2022.05.034"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.5812\/iranjradiol.117498"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.59556\/japi.72.0736"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000028721"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1742721"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-11002-0081"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781315113913-10"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-85730-7.00053-9"},{"issue":"5","key":"e_1_2_14_16_1","article-title":"Cytomegalovirus Cutaneous Infection in an Immunocompromised Patient","volume":"8","author":"Fasanya A. A.","year":"2016","journal-title":"Cureus"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7459"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1081\/CUS-120019329"},{"issue":"1","key":"e_1_2_14_19_1","first-page":"1","article-title":"Atypical Cutaneous Cytomegalovirus (CMV) Infections in Non\u2010AIDS Patients: A Report of 2 Cases","volume":"4","author":"Srisuttiyakorn C.","year":"2017","journal-title":"Clinical Research in Dermatology Open Access"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(98)70581-X"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/723962"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2011.1280"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-006-0361-8"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203320961473"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-233873"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(84)70234-9"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncprheum0269"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2016.2818"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2021.12.110"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1051\/mbcb\/2019006"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090882"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-022-02623-3"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(04)01202-2"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/0961203314532560"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.5070\/D3251042608"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10265-z"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07456.x"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2012.08.002"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2020.04.037"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.7459"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/92.1.96"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2021.104936"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/7854_2022_361"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.970168"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001084"},{"key":"e_1_2_14_46_1","unstructured":"R. R.PolamandS.ShaikA Review on Guillain\u2010Barre Syndrome (GBS).2021."},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.760889"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-020-05506-5"},{"key":"e_1_2_14_49_1","unstructured":"I.HecklerandM.SabalzaCytomegalovirus Infection: When and Why to Detect Antibodies."},{"key":"e_1_2_14_50_1","volume-title":"Cytomegalovirus Among Women of Reproductive Age: Newborn Screening Acceptability, Seroprevalence, and Viral Shedding","author":"Reinhart K. J.","year":"2023"}],"container-title":["Immunity, Inflammation and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iid3.70377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/iid3.70377","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iid3.70377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T05:16:57Z","timestamp":1776143817000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/iid3.70377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":49,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/iid3.70377"],"URL":"https:\/\/doi.org\/10.1002\/iid3.70377","archive":["Portico"],"relation":{},"ISSN":["2050-4527","2050-4527"],"issn-type":[{"value":"2050-4527","type":"print"},{"value":"2050-4527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2024-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70377"}}