{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:45:32Z","timestamp":1777632332199,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T00:00:00Z","timestamp":1776643200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82171642"],"award-info":[{"award-number":["82171642"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to evaluate the pregnancy outcomes of frozen embryo transfer (FET) in patients with persistent chronic endometritis (PCE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>186 patients were stratified into three groups: Cured CE (CCE), Cured Persistent CE (CPCE), and Still Persistent CE (SPCE). Only the first post\u2010treatment FET cycle per patient was analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among women aged 20\u201348, the biopsy\u2010based prevalence of CE and PCE was 14.23% and 1.30%, respectively. The SPCE group underwent more antibiotic treatments and endometrial pathology examinations, with a higher proportion of GnRH\u2010a\u2009+\u2009HRT cycles compared to the CCE and CPCE groups. Clinical pregnancy rates were 41.67%, 37.21%, and 52.17%, while live birth rates were 31.67%, 30.23%, and 43.48% for the CCE, CPCE, and SPCE groups, respectively. No statistically significant differences were observed among the groups. Multivariate analysis confirmed that AMH (aOR 1.135; 95% CI 1.005\u20131.282) and pre\u2010transfer endometrial thickness (aOR 1.259; 95% CI 1.07\u20131.49) are significantly associated with clinical pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our exploratory findings suggest that PCE may not necessarily impair FET outcomes under individualized management. Ovarian reserve and endometrial thickness appeared to be more robust predictors of success than histologic persistence in this cohort. Due to the small PCE sample size, these results are hypothesis\u2010generating and warrant validation in larger prospective trials.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Trial Registration<\/jats:title>\n                    <jats:p>\n                      This study is registered with China Medical Research Online (Registration Number: MR\u201044\u201024\u2010022293,\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.medicalresearch.org.cn\">www.medicalresearch.org.cn<\/jats:ext-link>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iid3.70448","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:37:20Z","timestamp":1776753440000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Retrospective Analysis of Pregnancy Outcomes Following Frozen Embryo Transfer in Patients With Persistent Chronic Endometritis: A Five\u2010Year Single\u2010Center Study"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5229-7860","authenticated-orcid":false,"given":"Yihua","family":"Liang","sequence":"first","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoyue","family":"Huang","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyan","family":"Lin","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Qiu","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuedan","family":"Jiao","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8166-7813","authenticated-orcid":false,"given":"Qingxue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Reproductive Medicine Centre, Sun Yat\u2010sen Memorial Hospital Sun Yat\u2010sen University Guangzhou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000529304"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jog.13937"},{"key":"e_1_2_12_4_1","first-page":"344","volume-title":"Fertility and Sterility","author":"Kitaya K.","year":"2018"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/1806-9282.20230792"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-024-02083-6"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.18821\/2313-8726-2018-5-1-19-25"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.25789\/YMJ.2023.82.02"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110706"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2022.103637"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2018.01.022"},{"key":"e_1_2_12_12_1","first-page":"413","volume-title":"Fertility & Sterility","author":"Xiong Y.","year":"2021"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.03.074"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-023-02902-z"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-022-02528-7"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13369"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/aji.13177"},{"key":"e_1_2_12_18_1","first-page":"1218","article-title":"Expert Consensus on Human Embryo Morphological Assessment: Cleavage\u2010Stage Embryos and Blastocysts Grading Criteria","volume":"42","author":"Li D.","year":"2022","journal-title":"Chinese Association of Reproductive Medicine"},{"key":"e_1_2_12_19_1","doi-asserted-by":"crossref","unstructured":"The Vienna Consensus: Report of An Expert Meeting on The Development of ART Laboratory Performance Indicators. 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