{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:41:01Z","timestamp":1782888061333,"version":"3.54.5"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:00:00Z","timestamp":1781136000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp; Disease"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Anti\u2010dipeptidyl\u2010peptidase\u2010like protein 6 encephalitis (DPPXE) is an exceptionally rare form of autoimmune encephalitis characterized by a highly heterogeneous clinical phenotype.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, we report a Chinese patient presenting with severe abdominal pain as a prominent symptom; furthermore, we conducted a systematic review and analysis of 125 cases of DPPXE (including the present case).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This rare case presented with severe abdominal pain as a prominent symptom. We comprehensively summarized the clinical presentations, patterns of recurrence, and therapeutic responses of DPPXE. Notably, by comparing the clinical characteristics of DPPXE cases reported in China with those from other regions, we found some differences in disease presentation, suggesting potential racial or geographic variability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings may provide up\u2010to\u2010date and comprehensive insights into the pathophysiology and clinical course of this rare disorder from multiple perspectives.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/iid3.70472","type":"journal-article","created":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T06:26:13Z","timestamp":1781245573000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe Abdominal Pain as a Prominent Clinical Manifestation of Anti\u2010DPPX Autoimmune Encephalitis: A Case Report and Systematic Review"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9252-4816","authenticated-orcid":false,"given":"Difang","family":"Shi","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery I, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital Peking University Cancer Hospital Yunnan Kunming Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haohao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baogang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianjian","family":"Bao","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengming","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Neurology Yunnan Qujing Central Hospital (Qujing First People's Hospital) Qujing Yunnan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,11]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2012.99"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23756"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/neuro.02.008.2008"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.08.008"},{"key":"e_1_2_16_6_1","first-page":"862","article-title":"Anti\u2010Dipeptidyl Peptidase\u2010Like Protein\u20106 Antibody Encephalitis","volume":"20","author":"Zhou Q. 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