{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T02:54:28Z","timestamp":1771383268189,"version":"3.50.1"},"reference-count":62,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T00:00:00Z","timestamp":1681257600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Background<\/jats:bold>: After introducing Covid\u201019 vaccines, a few side effects were reported, pityriasis rosea being one of them. Therefore, this study will systematically review its manifestation afteradministration.<jats:bold>Methods<\/jats:bold>: Databases were searched, covering a timeline from December 1, 2019 to February 28, 2022. Data were independently extracted and accessed for bias. SPSS statistical software version 25 was used for appropriate inferential statistics. <jats:bold>Results<\/jats:bold>: Thirty\u2010one studies were included for data extraction after screening following the eligibility criteria. A total of 111 people were identified to have developed pityriasis rosea or pityriasis rosea\u2010like eruptions after vaccination, out of which 36 (55.38%) were female. The average age of incidence was calculated to be 44.92 years, and 63 (62.37%) people presented after administration of the first dose. It was found popularly in the trunk area, either asymptomatically or with mild symptoms. Meantime the onset, was 8.58 days, and meantime it took to recover, was 6.44 weeks. <jats:bold>Conclusion<\/jats:bold>: The association between pityriasis rosea and pityriasis rosea\u2010like eruptions after Covid\u201019 vaccines was established, but given the scarcity of studies, there is a need to conduct different clinical trials to confirm this association further and study the etiology and mechanism of the disease.<\/jats:p>","DOI":"10.1002\/iid3.804","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T09:31:26Z","timestamp":1681291886000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Manifestation of pityriasis rosea and pityriasis rosea\u2010like eruptions after Covid\u201019 vaccine: A systematic review"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4717-8899","authenticated-orcid":false,"given":"Iman","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Medicine Ziauddin Medical University Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed A.","family":"Elsanousi","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Medical Science and Technology Khartoum Sudan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amena M.","family":"Shareef","sequence":"additional","affiliation":[{"name":"Department of Medicine Deccan College of Medical Sciences Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer S.","family":"Tebha","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery and Neurology Jinnah Medical and Dental College Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aabiya","family":"Arif","sequence":"additional","affiliation":[{"name":"Department of Medicine Ziauddin Medical University Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana","family":"Gul","sequence":"additional","affiliation":[{"name":"Department of Dermatology Jinnah Medical and Dental College Karachi Sindh Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,12]]},"reference":[{"issue":"1142","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/postgradmedj-2020-138234","article-title":"Origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID\u201019)","volume":"96","author":"Umakanthan S","year":"2020","journal-title":"Postgrad Med J"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-020-12070-7"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-021-00876-0"},{"key":"e_1_2_9_5_1","unstructured":"COVID\u201019 Map\u2014Johns Hopkins Coronavirus Resource Center. Accessed February 2 \u00a02022.https:\/\/coronavirus.jhu.edu\/map.html"},{"issue":"3","key":"e_1_2_9_6_1","first-page":"221","article-title":"Efficacy and safety of COVID\u201019 vaccines: a systematic review","volume":"23","author":"Xing K","year":"2021","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi"},{"key":"e_1_2_9_7_1","unstructured":"Side effects of COVID\u201019 vaccines. Accessed February 2 \u00a02022.https:\/\/www.who.int\/news-room\/feature-stories\/detail\/side-effects-of-covid-19-vaccines"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijd.IJD_682_16"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.18294"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20639"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1098-3597(01)90002-X"},{"key":"e_1_2_9_12_1","unstructured":"Herald Patch\u2014PubMed. Accessed February 2 \u00a02022.https:\/\/pubmed.ncbi.nlm.nih.gov\/30020673\/"},{"key":"e_1_2_9_13_1","unstructured":"Pityriasis rosea: background pathophysiology etiology. Accessed February 4 \u00a02022.https:\/\/emedicine.medscape.com\/article\/1107532-overview#a6"},{"key":"e_1_2_9_14_1","unstructured":"PRISMA. Accessed February 2 \u00a02022.http:\/\/www.prisma-statement.org\/"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14372"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17342"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2021.10.055"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2021.1963173"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17498"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.15700"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27364"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.09.002"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15256"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2021.12.028"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.20143"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15040"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17678"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17648"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17592"},{"issue":"25","key":"e_1_2_9_30_1","first-page":"431","article-title":"Pityriasis rosea as a possible complication of vaccination against COVID\u201019","volume":"118","author":"Dormann H","year":"2021","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2021.11.016"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/iid3.568"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15153"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocd.14592"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14104"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17343"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17633"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.12788\/cutis.0411"},{"key":"e_1_2_9_39_1","first-page":"e158","article-title":"Cutaneous adverse reactions from 35,229 doses of Sinovac and AstraZeneca COVID\u201019 vaccination: a prospective cohort study in healthcare workers","volume":"36","author":"Rerknimitr P","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdin.2022.01.009"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17951"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.3390\/dermatopathology8040049"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.15225"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17575"},{"key":"e_1_2_9_45_1","first-page":"1\u20102","article-title":"Pityriasis rosea induced by COVID\u201019 vaccination","volume":"9","author":"Khattab E","year":"2022","journal-title":"Eur\u00a0J\u00a0Case Rep\u00a0Internal Med"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.74974"},{"key":"e_1_2_9_47_1","unstructured":"Cell\u2010mediated immunity and the challenges for vaccine development\u2014PubMed. Accessed February 4 \u00a02022.https:\/\/pubmed.ncbi.nlm.nih.gov\/17055276\/"},{"key":"e_1_2_9_48_1","unstructured":"Pityriasis rosea: diagnosis and treatment\u2014PubMed. Accessed February 4 \u00a02022.https:\/\/pubmed.ncbi.nlm.nih.gov\/29365241\/"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13730"},{"key":"e_1_2_9_50_1","unstructured":"WHO Coronavirus (COVID\u201019) Dashboard. WHO coronavirus (COVID\u201019) dashboard with vaccination data. Accessed December 9 \u00a02022.https:\/\/covid19.who.int\/"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/iid3.404"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01076"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.4314\/nqjhm.v20i1.57989"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.05.030"},{"issue":"8","key":"e_1_2_9_55_1","article-title":"Pityriasis rosea like drug rash\u2014a need to identify the disease in childhood","volume":"8","author":"Panda M","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"e_1_2_9_56_1","unstructured":"Pityriasis rosea\u2014DermNet. Accessed February 4 \u00a02022.https:\/\/dermnetnz.org\/topics\/pityriasis-rosea"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdcr.2018.04.002"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v5.i6.203"},{"issue":"10","key":"e_1_2_9_59_1","first-page":"34","article-title":"Interventions for pityriasis rosea","volume":"2019","author":"Contreras\u2010Ruiz J","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/dth.14679"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2009.21.3.230"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.131457"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1159\/000363568"}],"container-title":["Immunity, Inflammation and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/iid3.804","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T18:11:32Z","timestamp":1744395092000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/iid3.804"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":62,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1002\/iid3.804"],"URL":"https:\/\/doi.org\/10.1002\/iid3.804","archive":["Portico"],"relation":{},"ISSN":["2050-4527","2050-4527"],"issn-type":[{"value":"2050-4527","type":"print"},{"value":"2050-4527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"2023-01-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e804"}}