{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:54:42Z","timestamp":1753869282545,"version":"3.41.2"},"reference-count":25,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Immunity Inflam &amp;amp; Disease"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To compare and analyze the clinical therapeutic effects of sodium hypochlorite combined with Nd: YAG laser and sodium hypochlorite alone for root canal disinfection in patients with pulpitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients with pulpitis were divided into control group and observation group according to random number table method. Both groups received root canal treatment, while the control group received root canal irrigation with 1% sodium hypochlorite. The observation group was irrigated with 1% sodium hypochlorite combined with Nd: YAG laser. Periodontal index, inflammatory index, life quality score and bacterial infection clearance rate of the two groups were compared before and 3 months after treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total effective rate of the observation group was 95.35%, which was higher than that of the control group 79.07% (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). After 3 months of treatment, the periodontal index and inflammation level of both groups decreased, and the observation group was lower than that in the control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). The life quality score and infection clearance rate of observation group were significantly higher than control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared with root canal irrigation with 1% sodium hypochlorite alone, sodium hypochlorite combined with Nd: YAG laser for root canal disinfection can significantly improve the therapeutic effect, relieve inflammatory reaction, and decrease bacterial infection.<\/jats:p><\/jats:sec>","DOI":"10.1002\/iid3.975","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T13:42:30Z","timestamp":1695735750000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analyze the clinical effect of YAG laser combined with sodium hypochlorite in root canal treatment of pulpitis"],"prefix":"10.1002","volume":"11","author":[{"given":"Qiaolin","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Stomatology Shijiazhuang Fourth Hospital  Shijiazhuang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhixin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Stomatology Shijiazhuang Fourth Hospital  Shijiazhuang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4040-560X","authenticated-orcid":false,"given":"Mingming","family":"Liu","sequence":"additional","affiliation":[{"name":"Laboratory Center The First Hospital of Hebei Medical University  Shijiazhuang China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","first-page":"S4","article-title":"Conservative pulp therapy in the management of reversible and irreversible 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