{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T04:56:44Z","timestamp":1769144204764,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2002,11,21]],"date-time":"2002-11-21T00:00:00Z","timestamp":1037836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2003,2,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The improving prognosis for children with cancer refocusses attention to long\u2010term outcomes with an emphasis on quality of life. Few studies have examined relationships and differences in reported results between the parent, child and clinician. We examined parent\u2010proxy and clinician\u2010reported functional status and health\u2010related quality of life for children and adolescents with acute lymphoblastic leukemia (ALL). Children and adolescents, 5\u201318 years, in the maintenance phase of treatment for ALL attending the Haematology\/Oncology outpatient clinic at the Royal Children's Hospital, Melbourne, were eligible. Measures included: 1) parent\u2010reported functional health and well\u2010being (Child Health Questionnaire [CHQ]); 2) parent\u2010reported condition specific quality of life (Pediatric Cancer Quality of Life inventory [PCQL]); 3) clinician ratings of physical and psychosocial health; and 4) clinical indicators. Insufficient numbers of older patients prohibited collection of adolescent self\u2010reports. We had a 94% response and 31 participants. Mean time since diagnosis: 1.5 (SD 0.4) years. Parents reported significantly lower functioning and well\u2010being than population norms for all CHQ scales, whereas cancer\u2010specific quality of life was comparable to PCQL norms. Clinician reports of the child's global physical and psychosocial health were moderately associated with each other (r<jats:sub>s<\/jats:sub> = 0.56, <jats:italic>p<\/jats:italic> &lt; 0.001), and with the parent\u2010reported physical (r<jats:sub>s<\/jats:sub> = 0.47, <jats:italic>p<\/jats:italic> &lt; 0.01) and psychosocial (r<jats:sub>s<\/jats:sub> = 0.56, <jats:italic>p<\/jats:italic> &lt; 0.001) CHQ summary scores. Clinician reports of the child's psychosocial health were not associated with any clinical indicators reported regularly. The results demonstrate that the social, physical and emotional health and well\u2010being of children with ALL is significantly poorer than the health of their community\u2010based peers. Routinely collected indicators of clinical progress conceal the psychosocial burden of ALL. Data on health, well\u2010being and quality of life can easily be incorporated into clinical care. \u00a9 2002 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.10815","type":"journal-article","created":{"date-parts":[[2002,12,12]],"date-time":"2002-12-12T14:09:22Z","timestamp":1039702162000},"page":"514-518","source":"Crossref","is-referenced-by-count":51,"title":["Health\u2010related quality of life of children with acute lymphoblastic leukaemia: Comparisons and correlations between parent and clinician reports"],"prefix":"10.1002","volume":"103","author":[{"given":"Elizabeth B.","family":"Waters","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa A.","family":"Wake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kylie D.","family":"Hesketh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Ashley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Smibert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,11,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.40.6.355"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.80.4.311"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008857920624"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1037\/0278-6133.12.3.246","article-title":"An investigation of the validity of the quality of well\u2010being scale with pediatric oncology patients","volume":"12","author":"Bradlyn AS","year":"1993","journal-title":"Health Psychol"},{"key":"e_1_2_6_6_2","first-page":"915","volume-title":"Childhood acute lymphoblastic leukaemia\u2010Part II. 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