{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T21:55:08Z","timestamp":1783634108106,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,3,2]],"date-time":"2004-03-02T00:00:00Z","timestamp":1078185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2004,6,20]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Preliminary data are available on the coexistence of primary hyperparathyroidism and breast carcinoma. To further understand the association between hyperparathyroidism and breast cancer, we conducted a record\u2010linkage study in Sweden using the Swedish Cancer Registry from 1958\u20131997. A total of 9,835 women who underwent surgery for primary parathyroid adenoma were followed to evaluate the hypothesis that a history of primary hyperparathyroidism increases the risk of subsequent breast cancer. During 99,929 person\u2010years of follow\u2010up, 331 cases of newly diagnosed breast cancer were reported. The number of expected breast cancers in this population was 260.0. This resulted in a standardized incidence ratio of 1.27 (95% confidence interval [CI] = 1.14\u20131.41). The relation persisted over time after the surgical removal of the parathyroid adenoma. Possible explanations for the observed association are a shared etiology including genetic and environmental factors such as early life radiation, and hypercalcemia after the overproduction of parathyroid hormone, which may increase breast cancer incidence. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.20155","type":"journal-article","created":{"date-parts":[[2004,3,25]],"date-time":"2004-03-25T16:54:12Z","timestamp":1080233652000},"page":"449-451","source":"Crossref","is-referenced-by-count":41,"title":["Hyperparathyroidism and subsequent incidence of breast cancer"],"prefix":"10.1002","volume":"110","author":[{"given":"Karin B.","family":"Michels","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lena","family":"Brandt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Ekbom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,3,2]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Cancer facts and figures 2002","author":"American Cancer Society","year":"2002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/152.10.950"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(76)90056-5"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1970.01340290038008"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(73)80046-7"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1986.tb02795.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF03343867"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5774.573"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1981.01380170035006"},{"key":"e_1_2_5_11_2","first-page":"3","article-title":"Overview of cancer\u2010related hypercalcemia: epidemiology and etiology. Review","volume":"17","author":"Muggia FM","year":"1990","journal-title":"Semin Oncol"},{"key":"e_1_2_5_12_2","volume-title":"Hypercalcemia of malignancy: etiology, pathogenesis, and clinical management","author":"Wimalawansa SJ","year":"1995"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198911093211902"},{"key":"e_1_2_5_14_2","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1001\/jama.1995.03530050050031","article-title":"Studies of cancer and radiation dose among atomic bomb survivors: the example of breast cancer","volume":"274","author":"Land CE","year":"1995","journal-title":"JAMA"},{"key":"e_1_2_5_15_2","first-page":"N18","article-title":"Epidemiology of primary hyperparathyroidism in Europe","volume":"17","author":"Adami S","year":"2002","journal-title":"J Bone Miner Res"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.3109\/02841868409136026"},{"key":"e_1_2_5_17_2","volume-title":"Cancer incidence in Sweden 1990","author":"Swedish Cancer Registry","year":"1993"},{"key":"e_1_2_5_18_2","volume-title":"Statistical methods in cancer research","author":"Breslow NE","year":"1987"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10846"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114879"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02966982"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2001.00849.x"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.20155","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.20155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T09:31:39Z","timestamp":1697189499000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.20155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3,2]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6,20]]}},"alternative-id":["10.1002\/ijc.20155"],"URL":"https:\/\/doi.org\/10.1002\/ijc.20155","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,3,2]]}}}