{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:20:16Z","timestamp":1792063216423,"version":"4.4.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T00:00:00Z","timestamp":1103241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Despite recent advances in the diagnosis and treatment of head and neck cancer, there has been little evidence of improvement in 5\u2010year survival rates over the last few decades. To determine more accurate trends in site\u2010specific outcomes as opposed to a more general overview of head and neck cancer patients, we analyzed the site\u2010specific data collected in the Surveillance, Epidemiology, and End Results\u2014SEER Public\u2010Use Database 1973\u20131999. Based on the selection criteria, 96,232 cases were evaluated for trend analysis in incidence, clinical stage, treatment and 5\u2010year survival. During the period 1973\u20131999, site\u2010specific incidence rates for head and neck cancer changed significantly. Site\u2010specific analysis of survival from 1974\u20131997 showed significant improvements in 5\u2010year survival rates for cancers of the nasopharynx, oropharynx and hypopharynx (38.1% to 56.7% for nasopharynx,\n                    <jats:italic>p<\/jats:italic>\n                    &lt; 0.001; 36.3% to 49.1% for oropharynx,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.001 and 28.3% to 33.3% for hypopharynx,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.015). The prognosis for early\u2010stage salivary gland cancer during 1983\u20131997 and late\u2010stage larynx cancer during 1974\u20131997 also demonstrated improvement (82.7% to 88.5%,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.012 and 22.2% to 38.3%,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.013, respectively). On the other hand, the prognosis for regional stage oral cavity cancer as well as early\u2010stage larynx cancer patients declined during 1983\u20131997 (49.2% to 43.8%,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.032 and 82.3% to 74.3%,\n                    <jats:italic>p<\/jats:italic>\n                    = 0.002, respectively). Site\u2010specific changes in treatment and staging were also noted. Site\u2010specific analysis allows for a more accurate description of incidence, staging, treatment, and prognostic trends for head and neck cancer. \u00a9 2004 Wiley\u2010Liss, Inc.\n                  <\/jats:p>","DOI":"10.1002\/ijc.20740","type":"journal-article","created":{"date-parts":[[2004,12,17]],"date-time":"2004-12-17T17:52:58Z","timestamp":1103305978000},"page":"806-816","source":"Crossref","is-referenced-by-count":709,"title":["Trends in incidence and prognosis for head and neck cancer in the United States: A site\u2010specific analysis of the SEER database"],"prefix":"10.1002","volume":"114","author":[{"given":"Andr\u00e9 Lopes","family":"Carvalho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00eas Nobuko","family":"Nishimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Califano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Paulo","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,2,18]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.54.1.8"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.52.1.23"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.48.4.199"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.45.6.352"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)90011-4"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra001375"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.52.4.195"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900501)65:9<1918::AID-CNCR2820650908>3.0.CO;2-B"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1054\/jcms.2000.0172"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(03)00138-6"},{"key":"e_1_2_6_12_2","unstructured":"National Cancer Institute. Surveillance Research Program Cancer Statistics Branch.SEER program public use data tapes 1973\u20131999. Release 2002."},{"key":"e_1_2_6_13_2","unstructured":"National Cancer Institute.http:\/\/seer.cancer.gov\/about\/2004."},{"key":"e_1_2_6_14_2","volume-title":"ICD\u201010: International statistical classification of diseases and related health problems, 1989 revision","year":"1992"},{"key":"e_1_2_6_15_2","unstructured":"Summary Staging Guide. Cancer Surveillance epidemiology and end results reporting.National Cancer Institute \u2010 National Institutes of Health 1977."},{"key":"e_1_2_6_16_2","volume-title":"AJCC Cancer Staging Manual","author":"American Joint Committee on Cancer","year":"2003"},{"key":"e_1_2_6_17_2","unstructured":"Surveillance Research Program National Cancer Institute. SEER*Stat software version 5.0.20.2003."},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.48.4.211"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(04)00090-X"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10571"},{"key":"e_1_2_6_21_2","unstructured":"SEER public access record description. Cases diagnosed in 1973\u201399 User File 2002."},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20071"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198506203122504"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/95.15.1105"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1368-8375(01)00109-9"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)01370-1"},{"key":"e_1_2_6_27_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-200206000-00002"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.20740","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.20740","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T15:43:46Z","timestamp":1696779826000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.20740"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,18]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["10.1002\/ijc.20740"],"URL":"https:\/\/doi.org\/10.1002\/ijc.20740","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,18]]}}}