{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T11:33:00Z","timestamp":1772105580967,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T00:00:00Z","timestamp":1160524800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2007,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Israeli Arabs have been at low risk for colorectal cancer (CRC) and had mainly proximal cancer, but increasing CRC is now noted. We examined this trend and CRC site and compared them to the total Jewish population and to the low\u2010risk Jews of Asian\u2010African origin. Israel Cancer Registry CRC data, 1982\u20132002, for Arabs and Jews was computed by gender, age and site: rectal cancer included recto\u2010sigmoid junction; \u201cright\u2010sided\u201d CRC included the proximal colon up to and also the splenic flexure. During 1982\u20132002, Arab CRC trends increased significantly in both sexes due to <jats:italic>left<\/jats:italic>\u2010sided CRC (women, <jats:italic>p<\/jats:italic> = 0.01; men, <jats:italic>p<\/jats:italic> = 0.02) and rectal cancers (<jats:italic>p<\/jats:italic> = 0.05). <jats:italic>Left<\/jats:italic>\u2010sided CRC increased significantly in both men and women aged \u2265 65 years (<jats:italic>p<\/jats:italic> = 0.02). Comparing 1982\u20131984 to 2000\u20132002, the proportion of right\u2010sided CRC decreased in both genders (<jats:italic>p<\/jats:italic> &lt; 0.01) from 39.4 to 27.1% of male CRC, and from 44.8 to 31.3% in females. In general, this pattern of increasing rectal and left\u2010sided CRC had been seen over a decade earlier in Jews of Asian\u2010African origin and then their trend reversed during the last decade. In conclusion, there is a recent trend for left\u2010sided CRC in Israeli Arabs, probably related to their changing life style. These results should influence their cancer preventive lifestyle recommendations, and CRC screening and diagnostic methodologies used. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.22141","type":"journal-article","created":{"date-parts":[[2006,10,11]],"date-time":"2006-10-11T20:33:30Z","timestamp":1160598810000},"page":"147-151","source":"Crossref","is-referenced-by-count":18,"title":["The changing incidence and sites of colorectal cancer in the Israeli Arab population and their clinical implications"],"prefix":"10.1002","volume":"120","author":[{"given":"Paul","family":"Rozen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Rosner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irena","family":"Liphshitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micha","family":"Barchana","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,10,11]]},"reference":[{"key":"e_1_2_6_2_2","series-title":"Cancer incidence in five continents","first-page":"362","author":"Parkin DM","year":"1998"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-004-9544-0"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-004-9546-y"},{"key":"e_1_2_6_5_2","unstructured":"YaffeN TalD. 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