{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T12:56:46Z","timestamp":1779195406590,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2006,8,7]],"date-time":"2006-08-07T00:00:00Z","timestamp":1154908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2006,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Sex is a consistent predictor of bladder cancer: men experience 2\u20134\u2010fold higher age\u2010adjusted rates than women in the U.S. and Europe. The objective of this study was to examine whether hormone\u2010related factors are associated with bladder cancer in women. We examined parity, age at menarche, age at first birth, age at menopause, oral contraceptive use and menopausal hormone therapy (HT) use and bladder cancer risk in the Breast Cancer Detection Demonstration Project Follow\u2010Up Study. Endpoint and exposure information was collected on 54,308 women, using annual telephone interviews (1980\u201386) and 3 mailed, self\u2010administered questionnaires (1987\u201398). During an average follow\u2010up time of 15.3 years, 167 cases of bladder cancer were identified. Univariate and adjusted rate ratios (RRs) were estimated using Poisson regression. Parity, age at menarche, age at first birth, age at menopause, and oral contraceptive use were not associated with bladder cancer risk. The majority of menopausal women who took HT used estrogen therapy (ET). Postmenopausal women with less than 4 years, 4\u20139 years, 10\u201319 years and 20 or more years of ET use had RRs of 1.55 (95% CI = 0.96\u20132.51), 1.00 (95% CI = 0.49\u20132.04), 1.23 (95% CI = 0.62\u20132.43) and 0.57 (95% CI = 0.14\u20132.34), respectively, compared with nonusers (<jats:italic>p<\/jats:italic> = 0.50). Findings from this study are not consistent with the hypothesis that hormone\u2010related factors in women are associated with bladder cancer. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.22175","type":"journal-article","created":{"date-parts":[[2006,8,7]],"date-time":"2006-08-07T18:17:50Z","timestamp":1154974670000},"page":"2398-2401","source":"Crossref","is-referenced-by-count":66,"title":["Reproductive factors, exogenous hormone use and bladder cancer risk in a prospective study"],"prefix":"10.1002","volume":"119","author":[{"given":"Marie M.","family":"Cantwell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"James V.","family":"Lacey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Schairer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arthur","family":"Schatzkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominique S.","family":"Michaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,9,26]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"Surveillance Epidemiology and End Results (SEER) Program.SEER 1975\u20102001. 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