{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:53:25Z","timestamp":1790128405436,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2007,10,12]],"date-time":"2007-10-12T00:00:00Z","timestamp":1192147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2008,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We investigated Hepatitis C virus (HCV) seropositivity and the risk of non\u2010Hodgkin lymphoma (NHL) in a population\u2010based case\u2010control study in British Columbia, Canada. Cases were aged 20\u201379, diagnosed between March 2000 and February 2004, and resident in greater Vancouver or Victoria. Cases with HIV or a prior transplant were excluded. Controls were chosen from the Client Registry of the British Columbia (BC) Ministry of Health, and were age\/sex\/region frequency matched to cases. Antibodies for HCV were measured in 795 cases and 697 control subjects. HCV seropositivity was 2.4% in cases and 0.7% in controls [odds ratio (OR) = 2.6, 95% confidence interval (CI) = 0.9\u20137.4]. A significantly elevated risk was observed for B\u2010cell lymphoma (OR = 2.9, 95%CI = 1.0\u20138.6). The highest risks were associated with diffuse large B\u2010cell lymphoma (OR = 7.3, 95%CI = 2.1\u201325.0) and marginal zone lymphoma (OR = 6.1, 95%CI = 1.1\u201333.9). Our results provide further evidence that HCV infection contributes to NHL risk. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.23105","type":"journal-article","created":{"date-parts":[[2007,10,12]],"date-time":"2007-10-12T15:17:12Z","timestamp":1192202232000},"page":"630-633","source":"Crossref","is-referenced-by-count":23,"title":["Hepatitis C virus and risk of non\u2010Hodgkin lymphoma in British Columbia, Canada"],"prefix":"10.1002","volume":"122","author":[{"given":"John J.","family":"Spinelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes S.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mel","family":"Krajden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Andonov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randy D.","family":"Gascoyne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph M.","family":"Connors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela R.","family":"Brooks\u2010Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Gallagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,26]]},"reference":[{"key":"e_1_2_6_2_2","volume-title":"SEER cancer statistics review, 1975\u20132003","author":"Ries L","year":"2005"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-05-0958"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.35620"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1191\/096120398678920091"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1191\/096120300678828127"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V82.12.3701.3701"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0308"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)90261-A"},{"key":"e_1_2_6_10_2","first-page":"425","article-title":"Hepatitis C\u2014global prevalence (update)","volume":"49","author":"World Health Organization","year":"1999","journal-title":"Wkly Epidemiol Rec"},{"key":"e_1_2_6_11_2","unstructured":"Health Canada. 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