{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:04:31Z","timestamp":1790795071743,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,6,10]],"date-time":"2008-06-10T00:00:00Z","timestamp":1213056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2008,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Neuroblastoma (NB), a tumor of the sympathetic nervous system, is the most common infant malignancy. The etiology of NB is largely unknown. We explored the association between birth record variables and subsequent NB development in a population\u2010based case\u2010cohort study in Minnesota by linking the birth and cancer registries. NB cases included 155 children born during 1976\u20132004 who were diagnosed from 28 days through 14 years of age. The comparison group included 8,752 individuals randomly sampled from the birth cohort of cases. Cox proportional hazards regression was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). Controlling for birth year and sex, maternal history of one fetal loss (HR = 1.7, 95% CI 1.2\u20132.5), maternal prenatal drug\u2010use (recorded starting in 1992) (HR = 5.7, 95% CI 2.3\u201314) and child's small size for gestational age (HR = 2.1, 95% CI 1.1\u20134.0) were significantly associated with NB. Age group specific analyses indicated that maternal hypertension (HR = 3.0, 95% CI 1.3\u20137.2) and maternal age &lt;20 years (HR = 2.6, 95% CI 1.1\u20136.1) increased risks for infant NB only. Our study provides evidence that a few perinatal exposures as recorded in birth records may play a role in NB etiology. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.23645","type":"journal-article","created":{"date-parts":[[2008,6,10]],"date-time":"2008-06-10T21:16:25Z","timestamp":1213132585000},"page":"1166-1172","source":"Crossref","is-referenced-by-count":34,"title":["Perinatal characteristics and risk of neuroblastoma"],"prefix":"10.1002","volume":"123","author":[{"given":"Kimberly J.","family":"Johnson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan E.","family":"Puumala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John T.","family":"Soler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Logan G.","family":"Spector","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,6,10]]},"reference":[{"key":"e_1_2_5_2_2","volume-title":"Cancer incidence and survival among children and adolescents: United States SEER Program 1975\u20131995","author":"Goodman MT","year":"1999"},{"key":"e_1_2_5_3_2","volume-title":"Neuroblastoma","author":"Brodeur GM","year":"2002"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60983-0"},{"key":"e_1_2_5_5_2","first-page":"967","article-title":"Parental smoking and alcohol consumption and risk of neuroblastoma","volume":"9","author":"Yang Q","year":"2000","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_5_6_2","first-page":"797","article-title":"Medical and drug risk factors associated with neuroblastoma: a case\u2010control study","volume":"78","author":"Kramer S","year":"1987","journal-title":"J Natl Cancer Inst"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3016.2001.00307.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116247"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/28.4.631"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00339-5"},{"key":"e_1_2_5_11_2","unstructured":"McLaughlinCC.Perinatal risk factors for childhood cancer. 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