{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:04:35Z","timestamp":1791338675416,"version":"4.3.1"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2008,9,2]],"date-time":"2008-09-02T00:00:00Z","timestamp":1220313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2008,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Endemic Burkitt lymphoma (BL) is etiologically associated with Epstein\u2010Barr virus and ecologically linked to <jats:italic>Plasmodium falciparum<\/jats:italic> malaria. However, these infections imperfectly correlate with BL epidemiology. To obtain recent epidemiological data, we studied district\u2010 and county\u2010specific BL incidence and standardized incidence ratios using data collected from 1997 to 2006 at Lacor Hospital in northern Uganda, where studies were last done more than 30 years ago. Among 500 patients, median age was 6 years (interquartile range 5\u20138) and male\u2010to\u2010female ratio was 1.8:1. Among those known, most presented with abdominal (56%, M:F 1.4:1) <jats:italic>vs.<\/jats:italic> only facial tumors (35%, M:F 3.0:1). Abdominal tumors occurred in older (mean age: 7.0 <jats:italic>vs.<\/jats:italic> 6.0 years; <jats:italic>p<\/jats:italic> &lt; 0.001) and more frequently in female children (68% <jats:italic>vs.<\/jats:italic> 50%; OR 2.2, 95% CI 1.5\u20133.5). The age\u2010standardized incidence was 2.4 per 100,000, being 0.6 in 1\u20134 year olds, 4.1 in 5\u20139 year olds and 2.8 in 10\u201314 year olds and varied 3\u2010 to 4\u2010fold across districts. The incidence was lower in districts that were far from Lacor and higher in districts that were close to Lacor. Although districts close to Lacor were also more urbanized, the incidence was higher in the nearby perirural areas. We highlight high\u2010BL incidence and geographic variation in neighboring districts in northern Uganda. Although distance from Lacor clearly influenced the patterns, the incidence was lower in municipal than in surrounding rural areas. Jaw tumors were characterized by young age and male gender, but presentation has shifted away from facial to mostly abdominal. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/ijc.23800","type":"journal-article","created":{"date-parts":[[2008,9,2]],"date-time":"2008-09-02T13:34:19Z","timestamp":1220362459000},"page":"2658-2663","source":"Crossref","is-referenced-by-count":82,"title":["Incidence and geographic distribution of endemic Burkitt lymphoma in northern Uganda revisited"],"prefix":"10.1002","volume":"123","author":[{"given":"Martin D.","family":"Ogwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kishor","family":"Bhatia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Biggar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam 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