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This article describes for the first time the use of fiber diffraction patterns of skin or fingernails, using X\u2010ray sources, as a biometric diagnostic method for detecting neoplastic disorders including but not limited to melanoma, breast, colon and prostate cancers. With suitable further development, an early low\u2010cost, totally noninvasive yet reliable diagnostic test could be conducted on a regular basis in local radiology facilities, as a confirmatory test for other diagnostic procedures or as a mass screening test using suitable small angle X\u2010ray beam\u2010lines at synchrotrons. \u00a9 2009 UICC<\/jats:p>","DOI":"10.1002\/ijc.24313","type":"journal-article","created":{"date-parts":[[2009,2,3]],"date-time":"2009-02-03T14:39:21Z","timestamp":1233671961000},"page":"133-138","source":"Crossref","is-referenced-by-count":20,"title":["Fiber diffraction of skin and nails provides an accurate diagnosis of malignancies"],"prefix":"10.1002","volume":"125","author":[{"given":"Veronica J.","family":"James","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,3,26]]},"reference":[{"key":"e_1_2_6_2_2","series-title":"International tables for crystallography","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1107\/97809553602060000702","author":"Chandrasekaran R","year":"2006"},{"key":"e_1_2_6_3_2","first-page":"272","volume-title":"Structure and dynamics of biomolecules","author":"Squire JM","year":"2000"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(01)00669-4"},{"key":"e_1_2_6_5_2","unstructured":"FeughelmanM WillisB JamesV.The tetrameric structure of the intermediate filaments of alpha\u2010keratin fibres. 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