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The aim of our study was to assess the association of alcohol consumption with CAG among older adults from Germany. In the baseline examination of ESTHER, a population\u2010based study conducted in Saarland, serological measurements of pepsinogen I and II (for CAG definition) and <jats:italic>H. pylori<\/jats:italic> antibodies were taken in 9,444 subjects aged 50\u201374 years. Moderate current (&lt;60 g\/week) and lifetime (\u226451,376 g, lowest quartile) alcohol consumption were found to be associated with significantly reduced CAG risk compared to alcohol abstinence with adjusted odds ratios of 0.71 (0.55\u20130.90) and 0.73 (0.55\u20130.96), respectively. Inverse associations with CAG were observed for moderate alcohol consumption from both beer and wine, and were slightly attenuated after additional adjustment for <jats:italic>H. pylori<\/jats:italic> infection. Our results are consistent with the hypothesis that moderate alcohol consumption may be inversely related to CAG, partly through facilitating the elimination of <jats:italic>H. pylori<\/jats:italic>. However, the observed patterns suggest that other mechanisms are likely to contribute to the association as well. \u00a9 2009 UICC<\/jats:p>","DOI":"10.1002\/ijc.24618","type":"journal-article","created":{"date-parts":[[2009,6,2]],"date-time":"2009-06-02T15:38:36Z","timestamp":1243957116000},"page":"2918-2922","source":"Crossref","is-referenced-by-count":30,"title":["Alcohol consumption and chronic atrophic gastritis: Population\u2010based study among 9,444 older adults from Germany"],"prefix":"10.1002","volume":"125","author":[{"given":"Lei","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie 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