{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:59:01Z","timestamp":1761292741685,"version":"3.38.0"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2010,10,26]],"date-time":"2010-10-26T00:00:00Z","timestamp":1288051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2011,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The objective of our study was to compare prospectively the QoL in long\u2010term ovarian cancer survivors with short\u2010term survivors and to explore discriminating variables between short\u2010term and long\u2010term survival. Thirty\u2010three patients were included, 22 died within 5 years post diagnosis and 11 survived beyond 10 years. QoL data were collected pre\u2010treatment (baseline), 1\u2010year post diagnoses and for long\u2010term survivors 10 years post\u2010treatment using the EORTC QLQ\u2010C30. At baseline, there was no difference in terms of FIGO stage, residual tumor and adjuvant chemotherapy. Significantly, more short\u2010term survivors (96%) had intra operative ascites as compared to long\u2010term survivors (55%) (<jats:italic>p<\/jats:italic>=0.01). Before treatment, short\u2010term survivors had clinically significantly lower QoL scores on the physical functioning (mean 75.45) and role functioning scale (mean 68.94) compared to long\u2010term survivors (mean 68.94 and 84.85, respectively). They also reported higher levels of symptoms. One year post\u2010diagnosis, QoL scores were comparable in most domains. Long\u2010term survivors had a significantly better global QoL but more insomnia. Emotional functioning and global QoL\/health status improved significantly from baseline to 1\u2010year post\u2010diagnosis and remained relatively stable at the 10\u2010year follow\u2010up. The presence of intra operative ascites and a supporting social network were identified as significant variables that discriminated between short\u2010term and long\u2010term survival. Compared to a reference sample, long\u2010term survivors showed similar QoL scores but more dyspnoea. Although ovarian cancer patients do not belong to the most prevalent survivor populations, we found that long\u2010term survivors have QoL scores similar to females without a history of cancer.<\/jats:p>","DOI":"10.1002\/ijc.25642","type":"journal-article","created":{"date-parts":[[2010,9,8]],"date-time":"2010-09-08T04:14:33Z","timestamp":1283919273000},"page":"3005-3011","source":"Crossref","is-referenced-by-count":29,"title":["Prospective assessment of quality of life in long\u2010term ovarian cancer survivors"],"prefix":"10.1002","volume":"128","author":[{"given":"Elfriede","family":"Greimel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fedor","family":"Daghofer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edgar","family":"Petru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,10,26]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.07.028"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1363"},{"key":"e_1_2_6_4_2","first-page":"401","article-title":"Comparison of the quality of life of early and advanced stage ovarian cancer survivors","volume":"115","author":"Mirabeau\u2010Beale KL","year":"2009","journal-title":"Gynecol Oncol"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2002.6812"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.08.150"},{"key":"e_1_2_6_7_2","first-page":"302","article-title":"Depression, anxiety, and quality of life in patients with epithelial ovarian cancer","volume":"78","author":"Bodurka\u2010Bevers D","year":"2000","journal-title":"J Clin Oncol"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.567"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11291"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.08.080"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.08.147"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.02.4067"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.11.034"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1438.2005.00141.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6199"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6437"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.1769"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1208"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.5.365"},{"volume-title":"Evaluation of chemotherapeutic agents in cancer","year":"1949","author":"Karnofsky DA","key":"e_1_2_6_20_2"},{"volume-title":"EORTC QLQ\u2010C30 scoring manual","year":"2001","author":"Fayers P","key":"e_1_2_6_21_2"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.1.139"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(00)00447-0"},{"volume-title":"Statistical power analysis for the behavioral sciences","year":"1988","author":"Cohen J","key":"e_1_2_6_24_2"},{"volume-title":"SPSS for windows, base system user's guide. 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