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Lifetime occupational history including work schedules of each night work period was elicited in 1,232 cases of breast cancer and 1,317 population controls. Thirteen percent of the cases and 11% of the controls had ever worked on night shifts (OR = 1.27 [95% confidence interval = 0.99\u20131.64]). Odds ratios were 1.35 [1.01\u20131.80] in women who worked on overnight shifts, 1.40 [1.01\u20131.92] in women who had worked at night for 4.5 or more years, and 1.43 [1.01\u20132.03] in those who worked less than three nights per week on average. The odds ratio was 1.95 [1.13\u20133.35] in women employed in night work for &gt;4 years before their first full\u2010term pregnancy, a period where mammary gland cells are incompletely differentiated and possibly more susceptible to circadian disruption effects. Our results support the hypothesis that night work plays a role in breast cancer, particularly in women who started working at night before first full\u2010term pregnancy.<\/jats:p>","DOI":"10.1002\/ijc.27669","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T08:59:37Z","timestamp":1339491577000},"page":"924-931","source":"Crossref","is-referenced-by-count":115,"title":["Night work and breast cancer: A population\u2010based case\u2013control study in France (the CECILE study)"],"prefix":"10.1002","volume":"132","author":[{"given":"Florence","family":"Menegaux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th\u00e9r\u00e8se","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoinette","family":"Anger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Cordina\u2010Duverger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farida","family":"Lamkarkach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Arveux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Kerbrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00eblle","family":"F\u00e9votte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Gu\u00e9nel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,6,26]]},"reference":[{"key":"e_1_2_5_2_2","unstructured":"IARC.Cancer incidence and mortality worldwidein2008. 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