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Incidence and follow\u2010up data on 23 cancer sites recorded at the Cancer Registry of Norway 1963\u20132007 were obtained. Mixture cure models were fitted to obtain trends and up\u2010to\u2010date estimates (based on period approach) assuming cured and uncured groups exist. The model converged for cancers of the mouth and pharynx, oesophagus, stomach, colon, rectum, liver, gallbladder, pancreas, lung and trachea, ovary, kidney, bladder, CNS, non\u2010Hodgkin lymphoma (only for males) and leukemia. The proportion of cured patients increased 1963\u20132002 for both sexes, with the largest changes (in percent) seen for leukemia (46.4 and 46.7) and CNS (35.9, 42.0), males given first. Median survival time for the uncured cases increased for colon and rectal cancer, and there was a three\u2010 fold increase in median survival time for patients with fatal ovarian cancers. Cancers of bladder and CNS had the highest up\u2010to\u2010date proportion cured (in percent), 67.4 and 64.0, respectively, pancreas and liver were amongst the lowest (5.7 and 9.9, respectively). Cure models are useful when monitoring progress in cancer care, but must be applied and interpreted with caution. The absolute estimates of the cure proportion are speculative and should not be calculated where cure is not medically anticipated.<\/jats:p>","DOI":"10.1002\/ijc.27802","type":"journal-article","created":{"date-parts":[[2012,8,28]],"date-time":"2012-08-28T05:53:07Z","timestamp":1346133187000},"page":"1700-1710","source":"Crossref","is-referenced-by-count":32,"title":["Proportion cured models applied to 23 cancer sites in Norway"],"prefix":"10.1002","volume":"132","author":[{"given":"Milada","family":"Cvancarova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarte","family":"Aagnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie D.","family":"Foss\u00e5","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f8rn","family":"M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Freddie","family":"Bray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,12,14]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdm127"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19990228)18:4<441::AID-SIM23>3.0.CO;2-M"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1304"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/1536867X0700700304"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.034"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22948"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604466"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.10.037"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-1046"},{"key":"e_1_2_5_11_2","first-page":"101","article-title":"The relative survival rate: a statistical methodology","volume":"6","author":"Ederer F","year":"1961","journal-title":"Natl Cancer Inst Monogr"},{"key":"e_1_2_5_12_2","article-title":"Estimating and modeling relative survival","author":"Dickman P","journal-title":"Stata J"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1597"},{"key":"e_1_2_5_14_2","first-page":"1965","volume-title":"patterns and trends in Norway","author":"Sm\u00e5stuen M","year":"2008"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwf071"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2003.10.013"},{"key":"e_1_2_5_17_2","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1200\/JCO.2002.20.3.826","article-title":"Up\u2010to\u2010date long\u2010term survival estimates of patients with cancer by period analysis","volume":"20","author":"Brenner H","year":"2002","journal-title":"J Clin Oncol"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.99.060"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/biostatistics\/kxl030"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1774"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1101"},{"key":"e_1_2_5_22_2","unstructured":"StataCorp. 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