{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T11:41:18Z","timestamp":1770550878831,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2012,10,12]],"date-time":"2012-10-12T00:00:00Z","timestamp":1350000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Incidence\u2010based evaluations of cervical cancer screening programs have suggested age\u2010specific impacts and there is uncertainty regarding the effectiveness of screening outside the ages of 30\u201360 years. We audited the screening histories of cervical cancer deaths and conducted a case\u2010control evaluation of the effectiveness of organized screening in different ages with mortality as outcome. We included all 506 cervical cancer deaths in Finland in 2000\u20132009 due to cancers diagnosed in 1990 or later, and 3,036 controls matched by age at diagnosis to the cases. Squamous cell carcinoma constituted 59% of the cases, adenocarcinomas 29%, and the remaining 12% were other specified and unspecified cervical malignancies. Most deaths (54%) were due to cancers diagnosed more than 5 years after last screening invitation, 24% were diagnosed among nonattenders and only 14% of deaths occurred among women who had attended invitational screening. The risk reduction associated with attending a single program screen at an age below 40 was nonsignificant (OR 0.70; 95% CI 0.33\u20131.48), while clear risk reductions were observed after screening at the age of 40\u201354 (OR 0.33; CI 0.20\u20130.56) and 55\u201369 (OR 0.29; CI 0.16\u20130.54). This study also provides some indication of a long\u2010lasting additional effect of screening at the age of 65. Possible avenues for improving the effectiveness of the Finnish screening program include efforts to increase attendance and an extension of the target ages to include 65\u2010to 69\u2010year\u2010old women. The potential benefit of increasing the sensitivity of the screening test or shortening the screening interval is smaller.<\/jats:p>","DOI":"10.1002\/ijc.27844","type":"journal-article","created":{"date-parts":[[2012,9,15]],"date-time":"2012-09-15T04:18:22Z","timestamp":1347682702000},"page":"2134-2140","source":"Crossref","is-referenced-by-count":47,"title":["Mortality audit of the Finnish cervical cancer screening program"],"prefix":"10.1002","volume":"132","author":[{"given":"Stefan","family":"L\u00f6nnberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pekka","family":"Nieminen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tapio","family":"Luostarinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahti","family":"Anttila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,12]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"302","volume-title":"IARC handbooks of cancer prevention: cervix cancer screening, vol. 10","author":"IARC","year":"2005"},{"key":"e_1_2_6_3_2","first-page":"172","article-title":"Age\u2010specific effectiveness of the Finnish cervical cancer screening programme","volume":"23","author":"L\u00f6nnberg S","year":"2012","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2968"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn099"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-6-252"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp367"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23276"},{"key":"e_1_2_6_9_2","first-page":"17","article-title":"Cervical cancer screening programme in Finland with an example on implementing alternative screening methods","author":"Anttila A","year":"2007","journal-title":"Coll Antropol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e900"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/1467-9876.00266"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600974"},{"key":"e_1_2_6_13_2","volume-title":"NORDCAN: cancer incidence, mortality, prevalence and survival in the nordic countries, Version 5.1 (March 2012): association of the nordic cancer registries","author":"Engholm G"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6601754"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24410"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a009721"},{"key":"e_1_2_6_17_2","unstructured":"Terveyden ja hyvinvoinnin laitos. Terveyden ja hyvinvoinnin laitoksen asettaman papilloomavirustautien torjuntaty\u00f6ryhm\u00e4n selvitys [Report of the study by the Expert Group on Papillomavirus Disease Prevention appointed by the National Institute for Health and Welfare]. Available at:http:\/\/www.thl.fi\/thl\u2010client\/pdfs\/94d6f45d\u201022e1\u20104b53\u2010b615\u20102eea48d90e1c."},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990924)83:1<55::AID-IJC11>3.0.CO;2-U"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.27844","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.27844","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T18:14:20Z","timestamp":1697480060000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.27844"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,12]]},"references-count":17,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["10.1002\/ijc.27844"],"URL":"https:\/\/doi.org\/10.1002\/ijc.27844","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,12]]}}}