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We determined the prevalence of 51 HPV types and three subtypes in 999 consecutive BD\u2010SurePath\u2122 liquid\u2010based cervical cytology samples collected during routine gynecological health checks from Belgian women. This series of screening samples was enriched with ASC\u2010US (<jats:italic>n<\/jats:italic> = 100), low\u2010grade squamous intraepithelial lesion LSIL (<jats:italic>n<\/jats:italic> = 100) and high\u2010grade squamous intraepithelial lesion (HSIL) (<jats:italic>n<\/jats:italic> = 97) and analyzed by BSGP5+\/6+\u2010PCR\/MPG assay for 51 HPV types and three subtypes. In consecutive screening samples, any of the 54 genital HPV (sub)types was found in 37.1%; Hr\u2010HPV types were detected more frequently (26.8%) than the 31 Lr\u2010HPV types (16.4%) and the six possibly high\u2010risk types (6.6%). High viral load infections were present in 17.0% of the screening population. Among the women with cytological abnormalities, the prevalence of high viral loads of Hr\u2010HPV types increased from negative for intraepithelial lesion or malignancy (NIL\/M) over ASC\u2010US, LSIL to HSIL (5.3, 47.1, 84.2 and 91.8%, respectively). The prevalence of possibly Hr and Lr\u2010HPV types increased from NIL\/M to LSIL but declined to HSIL. From NIL\/M to HSIL, Hr\u2010HPV infections showed an increasing frequency of high viral loads compared to total DNA positivity, but the increase between LSIL and HSIL was small. Type\u2010specific analyses revealed substantial differences between individual HPV types in these groups. Our study provides quantitative data for the whole spectrum of genital HPV in a Belgian screening population and in a representative set of women with cervical abnormalities.<\/jats:p>","DOI":"10.1002\/ijc.27891","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T06:51:12Z","timestamp":1349333472000},"page":"2395-2403","source":"Crossref","is-referenced-by-count":43,"title":["Prevalence and viral load of 51 genital human papillomavirus types and three 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