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The aim was to examine the excess in incidence of DCIS and IBC during the screening period and the deficit after women left the program, and thereby to estimate the proportion of overdiagnosis. Women invited to the Norwegian Breast Cancer Screening Program were analyzed for DCIS or IBC during the period 1995\u20132009. Incidence rate ratios (IRRs) were calculated for attended <jats:italic>vs<\/jats:italic>. never attended women. The IRRs were adjusted by Mantel\u2010Haenszel (MH) method and applied to a set of reference rates and a reference population to estimate the proportion of overdiagnosis during the women's lifespan after the age of 50 years. A total of 702,131 women were invited to the program. An excess of DCIS and IBC was observed among women who attended screening during the screening period; prevalently invited women aged 50\u201351 years had a MH IRR of 1.86 (95% CI 1.65\u20132.09) and subsequently invited women aged 52\u201369 years had a MH IRR of 1.56 (95% CI 1.45\u20131.68). In women aged 70\u201379 years, a deficit of 30% (MH IRR 0.70, 95% CI 0.62\u20130.80) was observed 1\u201310 years after they left the screening program. The estimated proportion of overdiagnosis varied from 10 to 20% depending on outcome and whether the women were invited or actually screened. The results highlight the need for individual data with longitudinal screening history and long\u2010term follow\u2010up as a basis for estimating overdiagnosis.<\/jats:p>","DOI":"10.1002\/ijc.28052","type":"journal-article","created":{"date-parts":[[2013,1,25]],"date-time":"2013-01-25T17:59:36Z","timestamp":1359136776000},"page":"705-712","source":"Crossref","is-referenced-by-count":57,"title":["Overdiagnosis among women attending a population\u2010based mammography screening program"],"prefix":"10.1002","volume":"133","author":[{"given":"Ragnhild S\u00f8rum","family":"Falk","sequence":"first","affiliation":[{"name":"Department of Research Cancer Registry of Norway  Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Solveig","family":"Hofvind","sequence":"additional","affiliation":[{"name":"Department of Research Cancer Registry of Norway  Norway"},{"name":"Faculty of Health Sciences Oslo and Akershus University College of Applied Science  Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Skaane","sequence":"additional","affiliation":[{"name":"Department of Radiology Oslo University Hospital Ullevaal University of Oslo  Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor","family":"Haldorsen","sequence":"additional","affiliation":[{"name":"Department of Research Cancer Registry of Norway  Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djm059"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2010.05.014"},{"key":"e_1_2_7_4_1","first-page":"229","volume-title":"IARC handbooks of cancer prevention. 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