{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:58:25Z","timestamp":1773295105748,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,3,4]],"date-time":"2013-03-04T00:00:00Z","timestamp":1362355200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[2013,8,15]]},"abstract":"<jats:p>Given the uncertainty surrounding solar ultraviolet radiation (UVR) exposure and risk of lymphoid neoplasms, we performed an ecological analysis of national Australian data for incident cases diagnosed between 2002 and 2006. Subtype\u2010specific incidence was examined by latitude band (&lt;29\u00b0S, 29\u201336\u00b0S, \u226537\u00b0S), a proxy for ambient UVR exposure, using multiple Poisson regression, adjusted for sex, age\u2010group and calendar year. Incidence increased with distance from the equator for several mature B\u2010cell non\u2010Hodgkin lymphomas, including diffuse large B\u2010cell [incidence rate ratio (IRR)\u2009=\u20091.37; 95% confidence interval (CI): 1.16\u20131.61 for latitude \u226537\u00b0S relative to &lt;29\u00b0S], lymphoplasmacytic (IRR\u2009=\u20091.34; 95% CI: 1.12\u20131.61), mucosa\u2010associated lymphoid tissue (IRR\u2009=\u20091.32; 95% CI: 0.97\u20131.80) and mantle cell lymphoma (IRR\u2009=\u20091.29; 95% CI: 1.05\u20131.58), as well as plasmacytoma (IRR\u2009=\u20091.52; 95% CI: 1.09\u20132.11) and plasma cell myeloma (IRR\u2009=\u20091.15; 95% CI: 1.03\u20131.27). A similar pattern was observed for several mature cutaneous T\u2010cell neoplasms, including primary cutaneous anaplastic large cell lymphoma (IRR\u2009=\u20094.26; 95% CI: 1.85\u20139.84), mycosis fungoides\/S\u00e9zary syndrome (IRR\u2009=\u20091.72; 95% CI: 1.20\u20132.46), and peripheral T\u2010cell lymphoma not otherwise specified (NOS) (IRR\u2009=\u20091.53; 95% CI: 1.17\u20132.00). Incidence of mixed cellularity\/lymphocyte\u2010depleted (IRR\u2009=\u20091.60; 95% CI: 1.16\u20132.20) and nodular sclerosis Hodgkin lymphoma (IRR\u2009=\u20091.57; 95% CI: 1.33\u20131.85) also increased with distance from the equator. Many of these subtypes have a known association with infection or immune dysregulation. Our findings support a possible protective effect of UVR exposure on the risk of several lymphoid neoplasms, possibly through vitamin D\u2010related immune modulation critical in lymphomagenesis.<\/jats:p>","DOI":"10.1002\/ijc.28081","type":"journal-article","created":{"date-parts":[[2013,2,5]],"date-time":"2013-02-05T08:36:43Z","timestamp":1360053403000},"page":"944-951","source":"Crossref","is-referenced-by-count":39,"title":["Latitude gradients for lymphoid neoplasm subtypes in Australia support an association with ultraviolet radiation exposure"],"prefix":"10.1002","volume":"133","author":[{"given":"Marina T.","family":"van Leeuwen","sequence":"first","affiliation":[{"name":"Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School The University of New South Wales Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer J.","family":"Turner","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Douglass Hanly Moir Pathology Macquarie University Sydney Australia"},{"name":"Australian School of Advanced Medicine Macquarie University Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael O.","family":"Falster","sequence":"additional","affiliation":[{"name":"Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School The University of New South Wales Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola S.","family":"Meagher","sequence":"additional","affiliation":[{"name":"Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School The University of New South Wales Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Joske","sequence":"additional","affiliation":[{"name":"Sir Charles Gairdner Hospital The University of Western Australia Perth Australia"},{"name":"School of Medicine and Pharmacology The University of Western Australia Perth Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew E.","family":"Grulich","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Centre Cancer Council Victoria Melbourne Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham G.","family":"Giles","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Centre Cancer Council Victoria Melbourne Australia"},{"name":"Centre for Molecular, Environmental, Genetic and Analytic Epidemiology The University of Melbourne Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire M.","family":"Vajdic","sequence":"additional","affiliation":[{"name":"Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School The University of New South Wales Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,4]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19920815)70:4<840::AID-CNCR2820700420>3.0.CO;2-I"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428199409049694"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.310.6993.1491"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7039.1128"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.169"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.7007.750a"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/88.5.298"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-6-264"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-03-0187"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.4161\/derm.2.2.13812"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2010.08.001"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.314.7092.1451"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-336065"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990301)80:5<641::AID-IJC1>3.0.CO;2-Z"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-011-9849-x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23003"},{"key":"e_1_2_7_18_1","first-page":"2687","article-title":"The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age\u2010adjusted cancer mortality rates","volume":"26","author":"Grant WB","year":"2006","journal-title":"Anticancer Res"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2004.tb09854.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25996"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2006.tb00086.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-06-289561"},{"key":"e_1_2_7_23_1","unstructured":"Australian Institute of Health and Welfare (AIHW) and Australasian Association of Cancer Registries.Cancer in Australia: an overview 2010. Cancer series no. 60. Cat. no. CAN 56. Canberra: AIHW; 2010."},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-10-0115"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dji022"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.22492"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyn092"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-1068"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1993.406"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.6674"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-295683"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602722"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3045"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70096-8"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-08-109611"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-04-347559"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra032810"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25272"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-08-368209"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/189096"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/2042-4280-2-8"},{"key":"e_1_2_7_42_1","unstructured":"Australian Bureau of Statistics. Australian social trends Sep 2012 \u201cTable 2: population state summary \u201d data cube: Excel spreadsheet cat. no. 4102.0. 26 September 2012. Available at:http:\/\/www.abs.gov.au\/AUSSTATS\/abs@.nsf\/DetailsPage\/4102.0Sep%202012?OpenDocument. Accessed 9 November 2012."},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq308"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27626"},{"key":"e_1_2_7_45_1","unstructured":"Cooke\u2010YarboroughC MulliganS ArcoraceM.Potentially significant under\u2010notification of chronic lymphocytic leukaemia\u2014results of a preliminary audit at NSW central cancer registryPaper Presented at the Australasian Epidemiological Association (AEA) Annual Scientific Meeting 2011."},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1562\/2005-02-15-IR-441"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2010.07.017"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2011.240432"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwq117"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2009.11.014"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2011.04320.x"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.28081","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.28081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T06:15:26Z","timestamp":1700633726000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.28081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,4]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,8,15]]}},"alternative-id":["10.1002\/ijc.28081"],"URL":"https:\/\/doi.org\/10.1002\/ijc.28081","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,4]]}}}