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The serum of a rabbit immunized with EB virus concentrate gave fair to very good blocking of the direct membrane reaction with the Mutua conjugate. The sera of rabbits immunized with chronic lymphatic leukemia cells were free of significant blocking activity. Sera of three rabbits immunized with Burkitt lymphoma biopsies gave significant blocking in several tests. It is concluded that the EBV\u2010determined surface antigen receptors can be distinguished from species\u2010specific membrane antigen sites and that this type of approach may be helpful to study the mutual relationships of antigenic structures identified by auto\u2010, allo\u2010 and heteroantibodies, respectively.<\/jats:p>","DOI":"10.1002\/ijc.2910040603","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T13:20:50Z","timestamp":1171891250000},"page":"761-766","source":"Crossref","is-referenced-by-count":10,"title":["Direct membrane fluorescence reaction of EBV\u2010carrying human lymphoblastoid cells: Blocking tests with xenogeneic antisera"],"prefix":"10.1002","volume":"4","author":[{"given":"Sven","family":"Bremberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.60.3.886"},{"key":"e_1_2_1_3_1","unstructured":"De Schryver A. Friberg S. Jr. Klein G. Henle W. Henle G. De Th\u00e9 G. Clifford P. andHo H. C. Epstein\u2010Barr virus (EBV)\u2010associated antibody patterns in carcinoma of the post\u2010nasal space.Clin. exp. Immunol. in press."},{"key":"e_1_2_1_4_1","first-page":"593","article-title":"Specific immunofluorescence test for EB\u2010virus; specific immunofluorescence test for the herpes\u2010type EB virus of Burkitt lymphoblasts, authenticated by electron microscopy","volume":"40","author":"Epstein M. A.","year":"1968","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_5_1","first-page":"749","article-title":"Direct membrane immunofluorescence reaction of Burkitt's lymphoma cells in culture","volume":"29","author":"Goldstein G.","year":"1969","journal-title":"Cancer Res."},{"key":"e_1_2_1_6_1","unstructured":"Hammond D. Mattiuz P. andCurtoni E. A. Histocompatibility testing pp.325\u2013332(1967)."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000386301"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","volume-title":"Burkitt's lymphoma","author":"Klein G.","DOI":"10.1016\/j.semcancer.2009.11.002"},{"key":"e_1_2_1_9_1","first-page":"1027","article-title":"Membrane immunofluorescence reactions of Burkitt lymphoma cells from biopsy specimens and tissue cultures","volume":"39","author":"Klein G.","year":"1967","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/36.4.607"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.129.4.697"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.128.5.1011"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196901)23:1<64::AID-CNCR2820230107>3.0.CO;2-M"},{"key":"e_1_2_1_14_1","first-page":"85","volume-title":"Proceedings of the Conference on Cross Reacting Antigens and Neo\u2010Antigens","author":"Roizman B.","year":"1967"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(68)90530-8"},{"key":"e_1_2_1_16_1","unstructured":"Van Loghem J. J. Immunosuppression by heterologous antibody. In:International Convocation on Immunology Buffalo S.Karger Basel\u2010New York in press."}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910040603","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910040603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T12:53:23Z","timestamp":1699793603000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910040603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,11,15]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1969,11,15]]}},"alternative-id":["10.1002\/ijc.2910040603"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910040603","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,11,15]]}}}