{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T16:29:36Z","timestamp":1758817776791},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2006,7,21]],"date-time":"2006-07-21T00:00:00Z","timestamp":1153440000000},"content-version":"vor","delay-in-days":11024,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1976,5,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Human serum pregnancy\u2010specific beta<jats:sub>1<\/jats:sub>\u2010globulin (beta<jats:sub>1<\/jats:sub>\u2010GP) was localized in paraffin sections of placenta and chorioepithelioma of the uterus by indirect immunofluorescence. The structures containing beta<jats:sub>1<\/jats:sub>\u2010GP but not human serum albumin were regarded as specifically associated with beta<jats:sub>1<\/jats:sub>\u2010GP metabolism. Beta<jats:sub>1<\/jats:sub>\u2010GP was found in trophoblastic cells of chorion and Langhans cells of chorioepithelioma. Using the immunoautoradiographic method (I<jats:sup>131<\/jats:sup>), we only found beta<jats:sub>1<\/jats:sub>\u2010GP in sera of patients with trophoblastic tumours: in 74.3% of 35 patients with chorioepithelioma and in 80% of 25 patients with hydatidiform mole and destructive hydatidiform mole. The diagnostic and prognostic significance of the immunochemical test for beta<jats:sub>1<\/jats:sub>\u2010GP in trophoblastic tumours is discussed.<\/jats:p>","DOI":"10.1002\/ijc.2910170511","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:01:22Z","timestamp":1171900882000},"page":"626-632","source":"Crossref","is-referenced-by-count":23,"title":["Human pregnancy\u2010specific beta<sub>1<\/sub>\u2010globulin and its relation to chorioepithelioma"],"prefix":"10.1002","volume":"17","author":[{"given":"Yu. S.","family":"Tatarinov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Falaleeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. 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