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Lymphoid cells from BALB\/c lymph nodes were then added to the peritioneal cells. Following 4\u20105 days of co\u2010cultivation, the lymphoid cells were harvested and tested in a 30 h microcytotoxicity assay for reactivity against tumor cells carrying the respective sensitizing antigens as well as against control cells which consisted of either tumor cells lacking the sensitizing antigens or normal skin fibroblasts. By this approach sensitization to individually unique tumor antigens, as well as to antigens shared by mouse embryos and mouse sarcoma cells, was achieved.<\/jats:p>","DOI":"10.1002\/ijc.2910170610","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:01:18Z","timestamp":1171900878000},"page":"748-754","source":"Crossref","is-referenced-by-count":12,"title":["Specific sensitization of lymphocytes to tumor antigens by Co\u2010cultivation with peritoneal cells exposed to such antigens"],"prefix":"10.1002","volume":"17","author":[{"given":"Ingegerd","family":"Hellstr\u00f6m","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl Erik","family":"Hellstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-230X(08)60750-2"},{"key":"e_1_2_1_3_1","doi-asserted-by":"crossref","unstructured":"Brown J. P. Van Belle G. andHellstr\u00f6m I. Design of experiments using the microcytotoxicity assay. Submitted toInt. J. Cancer(1976).","DOI":"10.1002\/ijc.2910180213"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(74)90138-5"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-107750-1.50035-2"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","unstructured":"Hellstr\u00f6m I. andHellstr\u00f6m K. E. Demonstration of tumor\u2010associated immunity with a leukocyte adherence inhibition (LAI) assay. Submitted toInt. J. 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