{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T00:07:10Z","timestamp":1699834030147},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":10716,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1977,3,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Three groups of EBV antigens, VCA, MA and EA, were compared by the techniques of electron microscopic immunoperoxidase (IP) and immuno\u2010fluorescence (IF). P3HR\u20101 and EBV superinfected Raji cells served as targets for labelled sera from patients with BL, NPC and IM or from healthy donors. <jats:sup>125<\/jats:sup>I peroxidase\u2010labelled antibodies were also prepared to determine, autoradiographically, the penetration of the complex into the cell system, and to monitor the incubation and washing procedures. The development of a gentle sedimentation technique proved critical in handling the fragile target cells. VCA and MA were readily identified and localized by both procedures without significant modification of the basic techniques. Indentification of early antigens by IP required modification of the fixation method to include a brief treatment in acetone. The diffuse early antigen (EAD) was found to be associated with cellular ribosomes.<\/jats:p>","DOI":"10.1002\/ijc.2910190305","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:25:43Z","timestamp":1171902343000},"page":"305-316","source":"Crossref","is-referenced-by-count":7,"title":["Comparative studies on ebv antigens by immuno\u2010fluorescence and immunoperoxidase techniques"],"prefix":"10.1002","volume":"19","author":[{"given":"R.","family":"Stephens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Traul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Gaudreau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. A.","family":"Mayyasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","volume-title":"Treatment of Burkitt's tumor","author":"Burkitt D. P.","year":"1967"},{"key":"e_1_2_1_3_1","volume-title":"Burkitt's lymphoma","author":"Burkitt D. P.","year":"1970"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.15.2.173"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(64)91524-7"},{"key":"e_1_2_1_6_1","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/jnci\/53.1.61","article-title":"Differentiation between early and late membrane antigen on human lymphoblastoid cell lines infected with Epstein\u2010Barr virus. I. Immunofluorescence","volume":"53","author":"Ernberg I.","year":"1974","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_7_1","first-page":"75","article-title":"Immunoferritin and immunofluorescence studies with Epstein\u2010Barr virus and Herpes simplex virus by use of human sera and hyperimmune rabbit sera","volume":"45","author":"Hampar B.","year":"1970","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_8_1","first-page":"248","volume-title":"The herpesviruses","author":"Hampar B.","year":"1973"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.91.3.1248-1256.1966"},{"key":"e_1_2_1_10_1","series-title":"International Agency for Research on Cancer Scientific Publication No. 11","first-page":"215","volume-title":"Oncogenesis and herpesviruses, II","author":"Henle W.","year":"1975"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.59.1.94"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910080212"},{"key":"e_1_2_1_13_1","first-page":"608","volume-title":"Handbook of experimental immunology","author":"Hunter W. M.","year":"1967"},{"key":"e_1_2_1_14_1","first-page":"39","article-title":"Reactivity of radioiodinated serum antibody from Burkitt lymphoma nasopharyngeal carcinoma patients against culture lines derived from Burkitt lymphoma","volume":"7","author":"Inoue M.","year":"1970","journal-title":"Clin. exp. Immunol."},{"key":"e_1_2_1_15_1","first-page":"521","volume-title":"The herpesviruses","author":"Klein G.","year":"1973"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.55.6.1628"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.128.5.1021"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.128.5.1011"},{"key":"e_1_2_1_19_1","first-page":"423","volume-title":"Methods in virology","author":"Kurstak E.","year":"1971"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910110302"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1128\/am.23.5.1001-1009.1972","article-title":"Immunoperoxidase localization of Herpes zoster virus and simian virus 40 in cell culture","volume":"23","author":"Shabo A. L.","year":"1972","journal-title":"Appl. Microbiol."},{"key":"e_1_2_1_22_1","volume-title":"33rd Ann. Proc. Electron Microscopy Soc. Amer.","author":"Stephens R.","year":"1975"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910150412"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910190305","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910190305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T08:05:27Z","timestamp":1699776327000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910190305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,3,15]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1977,3,15]]}},"alternative-id":["10.1002\/ijc.2910190305"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910190305","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,3,15]]}}}