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Response to EB virion (\u201cv\u201d) antigen was generally present at the time of diagnosis in the IM patients but the response to EB soluble (\u201cS\u201d) antigen was delayed. An increased CMI response to \u201cv\u201d antigen was found in patients with IM, Hodgkin's disease and non\u2010Hodgkin's lymphoma as compared to controls with and without cancer. Patients with Hodgkin's disease had depressed responses to the EBV\u2010associated \u201cS\u201d antigen. The finding of increased LAI responses to \u201cv\u201d antigen in Hodgkin's disease patients with high EBV antibody titers conflicts with previous reports attributing high antibody responses against EBV to a generalized depressed cell\u2010mediated immunity.<\/jats:p>","DOI":"10.1002\/ijc.2910190312","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:25:43Z","timestamp":1171902343000},"page":"356-363","source":"Crossref","is-referenced-by-count":12,"title":["Lymphocyte responses to ebv\u2010associated antigens in infectious mononucleosis, and hodgkin's and non\u2010hodgkin's lymphoma patients, with the leukocyte adherence inhibition assay"],"prefix":"10.1002","volume":"19","author":[{"given":"S. H.","family":"Chan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. H.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. 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