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The age distributions of patients with warts induced by HPV 1\u20103 or by HPV\u20104, respectively, differ markedly. HPV 1\u20103 predominates between 5 and 15 years of age, whereas HPV\u20104 could be isolated more often between the ages of 20\u201025 years. The large number of HPV\u20101\u20103\u2010induced warts in children is paralleled by a high percentage of HPV\u20101 antibody\u2010positive sera in the same age group (about 50%). With increasing age the percentage of HPV\u20101 antibody\u2010positive sera declines gradually. This pattern of seroreactivity was compared to that of patients with various papillomas and with several malignant tumors. There is no evidence to suggest a link between HPV 1\u20103 and <jats:italic>condylomata acuminata<\/jats:italic>, laryngeal papillomas or any of the malignant tumors tested.<\/jats:p>","DOI":"10.1002\/ijc.2910210206","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T17:03:41Z","timestamp":1171904621000},"page":"161-165","source":"Crossref","is-referenced-by-count":77,"title":["Seroepidemiological studies of human papilloma virus (HPV\u20101) infections"],"prefix":"10.1002","volume":"21","author":[{"given":"Herbert","family":"Pfister","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald Zur","family":"Hausen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(65)90633-1"},{"key":"e_1_2_1_3_1","first-page":"80","article-title":"Beitrag zur Epidemiologie der Warzen","volume":"15","author":"Bosse K.","year":"1964","journal-title":"Hautarzt"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022172400022531"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.4.1310"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(77)90239-2"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(66)91925-8"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj0890114"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910110128"},{"key":"e_1_2_1_10_1","first-page":"237","article-title":"Epstein\u2010Barr virus (EBV)\u2010associated antibody patterns in relation to the deficiency of cell\u2010mediated immunity in patients with Hodgkin's disease","volume":"11","author":"Johansson B.","year":"1975","journal-title":"Onc. 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