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Also, rabbit antisera were prepared to the Epstein\u2010Barr virus nuclear antigen (EBNA) and the early antigen (EA) and utilized in an indirect immunofluorescence test (IIT) to detect these antigens in human lymphocytes isolated from various disease states. Using these methods we demonstrated excellent correlation between standard methods previously employed to detect EB virus\u2010coded antigens and our IIT employing xenogenic antisera. Such tests were done on lymphoblastoid cell lines as well as lymphocytes isolated directly from patients with EB vims lymphoproliferative diseases. Human palatine tonsil\u2010derived lymphocytes from children with exudative tonsillitis and peripheral blood lymphocytes of infectious mononucleosis contained only EBNA in C3 receptor\u2010bearing B lymphocytes. However, patients with lymphoproliferative disorders, including Hodgkin's disease, harbored in their spleens and lymph nodes lymphocytes producing both EBNA and EA.<\/jats:p>","DOI":"10.1002\/ijc.2910210603","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T17:08:42Z","timestamp":1171904922000},"page":"683-687","source":"Crossref","is-referenced-by-count":11,"title":["EBV antigens in lymphocytes of patients with exudative tonsillitis, infectious mononucleosis and hodgkin's disease"],"prefix":"10.1002","volume":"21","author":[{"given":"Robert W.","family":"Veltri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James E.","family":"McClung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip M.","family":"Sprinkle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-28-2-219"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197402142900704"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196504)18:4<522::AID-CNCR2820180418>3.0.CO;2-J"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910190306"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.3.960"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.59.1.94"},{"key":"e_1_2_1_8_1","first-page":"861","article-title":"Antibodies to early Epstein\u2010Barr virus induced antigens in Burkitt's lymphoma","volume":"46","author":"Henle G.","year":"1971","journal-title":"J. nat. 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