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The 31 tumors were separable into four groups: (1) Tumors with normal karyotypes (three cases); (2) tumors with simple gains of chromosomes (three cases); (3) tumors with gains, losses and structural aberrations (ten cases). Groups 1, 2 and 3 were all in the diploid range; and (4) tumors with hypotriploid\u2010hypotetraploid karyotypes (15 cases). Non\u2010random gains of several chromosomes, especially No. 8 and non\u2010random losses of No. 17 were seen in this series. Thirteen cases had sex chromosome abnormalities. The most prominent structural abnormalities involved chomosomes No. 1 and No. 5. Marker chromosomes were sometimes absent, but when present ranged from simple translocations to the most complex rearrangements. Doubling of chromosome and\/or marker chromosomes were prominent in Group 4. Double minutes were seen in all three metastatic tumors and three primary cancers. Premature chromosome condensation was observed in three cases in the hypotriploid\u2010hypotetraploid group.<\/jats:p>","DOI":"10.1002\/ijc.2910280407","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T18:53:19Z","timestamp":1171911199000},"page":"431-440","source":"Crossref","is-referenced-by-count":109,"title":["Chromosomal banding patterns in human large bowel cancer"],"prefix":"10.1002","volume":"28","author":[{"given":"Amelia","family":"Reichmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulette","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Levin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"375","volume-title":"Chromosomes and Cancer","author":"Atkin N. 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