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Cultures from 10 normal seropositive donors all showed the normal pattern of regression. Lymphocytes from patients receiving Cyclosporin A therapy with or without prednisolone completely failed to cause regression, thus allowing B\u2010cell lines to proliferate unchecked. Cells from two of 17 patients treated with azathioprine and prednisone also failed to cause regression. The cells from the remaining 15 individuals showed regression responses varying from minimal to normal. These results suggest a mechanism by which EB virus\u2010related tumours may arise in immunosuppressed renal allograft recipients.<\/jats:p>","DOI":"10.1002\/ijc.2910280608","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T18:48:57Z","timestamp":1171910937000},"page":"705-709","source":"Crossref","is-referenced-by-count":52,"title":["Studies on long\u2010term T\u2010cell\u2010mediated immunity to epstein\u2010barr virus in immunosuppressed renal allograft recipients"],"prefix":"10.1002","volume":"28","author":[{"given":"D. H.","family":"Crawford","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M. B.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sweny","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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