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No papillomavirus DNA was identified in the two other tumors. All three invasively growing giant condylomata acuminata (Buschke\u2010L\u00f6wenstein tumors) investigated also contained HPV 6 DNA. Two out of six atypical condylomata of the cervix hybridized with HPV 6 DNA under stringent conditions, one only under conditions of low stringency. All DNA preparations from malignant tumors studied (54 cervical carcinomas, 10 penile carcinomas, two vulvar carcinomas) failed to anneal with HPV 6 DNA, even under conditions of low stringency. Although all HPV 6\u2010positive condylomata acuminata analyzed in this study revealed HPV 6 DNA of regular molecular weight (5.1 \u00d7 10<jats:sup>6<\/jats:sup>), two of the Buschke\u2010L\u00f6wenstein tumors, as well as one of the two positive atypical condylomata of the cervix, contained HPV 6 DNA with a remarkable size hetergeneity. Apparently all size classes occurred in a supercoiled form without evidence for integration into host cell DNA.<\/jats:p>","DOI":"10.1002\/ijc.2910290205","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T18:45:35Z","timestamp":1171910735000},"page":"143-146","source":"Crossref","is-referenced-by-count":272,"title":["Analysis of human genital warts (condylomata acuminata) and other genital tumors for human papillomavirus type 6 DNA"],"prefix":"10.1002","volume":"29","author":[{"given":"Lutz","family":"Gissmann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethel\u2010Michele","family":"De Villiers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald Zur","family":"Hausen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01910262"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.62.4.1159"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(66)90447-5"},{"key":"e_1_2_1_5_1","article-title":"Molecular cloning of viral DNA from human genital warts","volume":"40","author":"De Villiers E.\u2010M.","year":"1981","journal-title":"J. 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