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DNA damage as measured by alkaline elution and protein degradation were both induced by hyperthermia. However, the relationship of such damage to cell death is not yet clear. Our data indicate that hyperthermia either alone or in combination with X\u2010ray treatment should be a safe method of cancer therapy.<\/jats:p>","DOI":"10.1002\/ijc.2910330411","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T19:57:09Z","timestamp":1171915029000},"page":"483-489","source":"Crossref","is-referenced-by-count":11,"title":["Simultaneous hyperthermia at 43\u00b0c reduces radiation\u2010induced malignant transformation frequencies in golden hamster embryo cells"],"prefix":"10.1002","volume":"33","author":[{"given":"Masami","family":"Watanabe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Nikaido","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsutomu","family":"Sugahara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,20]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.2307\/3573997"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.2307\/3573947"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/252499a0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.2307\/3575545"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.2307\/3575650"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1148\/123.2.497"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/123.2.475"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.2307\/3576104"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1148\/123.2.463"},{"key":"e_1_2_1_11_1","first-page":"134","volume-title":"Proc. of Int. 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