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Analysis using monoclonal antibodies produced against the common placental alkaline phosphatase (PLAP) phenotypes and enzyme inhibition studies with amino acids and peptides showed the PLAP\u2010like enzymes present in seminoma to be similar to those PLAP\u2010like enzymes which are expressed in lower amounts in two embryonal carcinomas and in trace amounts in normal testicular tissue. These similarities suggest that the increased expression of PLAP\u2010like enzymes in seminomas results from enhanced eutopic expression of enzymes found in normal testis.<\/jats:p>","DOI":"10.1002\/ijc.2910340604","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T19:40:09Z","timestamp":1171914009000},"page":"757-761","source":"Crossref","is-referenced-by-count":27,"title":["Eutopic expression of placental\u2010like alkaline phosphatase in testicular tumors"],"prefix":"10.1002","volume":"34","author":[{"given":"A.","family":"Jeppsson","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Wahren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Brehmer\u2010Andersson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Silfversw\u00e4rd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Stigbrand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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