{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T16:42:07Z","timestamp":1726245727229},"reference-count":30,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":7154,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1986,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The expression of receptors for proliferation and differentiation factors was analyzed by indirect immunofluorescence on 29 Burkitt lymphoma (BL) cell lines previously Classified into 3 groups on the basis of their reactivity with 8 monoclonal antibodies (MAbs), including anti\u2010CALLA, BL<jats:sub>13<\/jats:sub> and T\u00dc<jats:sub>1<\/jats:sub>. BL<jats:sub>13<\/jats:sub> and HB<jats:sub>5<\/jats:sub>antibodies recognize different epitopes of the EBV\/CR<jats:sub>2<\/jats:sub> receptors. The determinant recognized by BL<jats:sub>13<\/jats:sub>has been previously shown to be expressed only on cell lines of the first two groups, supposed to derive from the germinal center and to be negative on a third group of lines of putative BM origin and established from sporadic cases of BL. In contrast, and as expected from its reactivity on normal B cells in the BM or in the lymph nodes, HB<jats:sub>5<\/jats:sub> antibody reacts with all BL lines except one. The receptor for transferrin is expressed on the 29 lines. Two new MAbs, Bac\u20101 and B<jats:sub>1<\/jats:sub>H<jats:sub>5<\/jats:sub>, could recognize respectively receptors for BCGF1 and BCGF2. Bac\u20101 reacts with 15 of 17 BL lines belonging to the first two groups and 7 of 12 BL lines of the third group; 14 of 15 EBV+ lines express Bac\u20101. No BL line expresses B<jats:sub>1<\/jats:sub>H<jats:sub>5<\/jats:sub>. The IL2 receptor is weakly expiressed on 5 EBV + cell lines and one EBV (\u2212) line. All 6 are BCGF1\u2010positive. The almost constant expression of BCGFI receptor on EBV+ cell lines is the only strict relation between the expression of receptors for growth factors and their characteristics (<jats:italic>i.e.<\/jats:italic> EBV association, translocation, ethnic origin and clinical presentation). The maturation stage or the origin of BL cell lines in relation to the expression of growth factor receptors and the functional significance of these receptors will be discussed.<\/jats:p>","DOI":"10.1002\/ijc.2910380618","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T20:47:12Z","timestamp":1171918032000},"page":"901-906","source":"Crossref","is-referenced-by-count":20,"title":["EBV\u2010negative and \u2010positive burkitt cell lines variably express receptors for B\u2010cell activation and differentiation"],"prefix":"10.1002","volume":"38","author":[{"given":"M. C.","family":"Favrot","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Maritaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Philip","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Philip","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Lenoir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830150407"},{"key":"e_1_2_1_3_1","first-page":"601","article-title":"Histopathological definition of Burkitt's tumour","volume":"40","author":"Berard C.","year":"1969","journal-title":"Bull. WHO"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.18004619704"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910330407"},{"key":"e_1_2_1_6_1","first-page":"59","article-title":"T cell regeneration after allogeneic bone marrow transplantation","volume":"54","author":"Favrot M.","year":"1983","journal-title":"Clin. exp. Immunol."},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92262-1"},{"key":"e_1_2_1_8_1","first-page":"841","article-title":"Distinct reactivity of Burkitt cell lines with eight monoclonal antibodies correlated with the ethnic origin","volume":"73","author":"Favrot M. C.","year":"1984","journal-title":"J. not. Cancer Inst."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830150114"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910340615"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910350218"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.127.1.347"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.160.5.1597"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.4049\/jimmunol.130.4.1985","article-title":"Induction of an activated B lymphocyte\u2010associated surface moiety defined by the B2 monoclonal antibody by EBV conversion of an EBV\u2010negative lymphoma line (Ramos): differential effect of transforming (B95\u20138) and nontransforming (P3HR\u20101) EBV substrains","volume":"130","author":"Klein G.","year":"1983","journal-title":"J. Immunol."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.14.4522"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.161.5.1225"},{"key":"e_1_2_1_17_1","first-page":"283","volume-title":"Pathogenesis of leukemias and lytnphomas; environmental influences","author":"Lenoir G. M.","year":"1984"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/298474a0"},{"key":"e_1_2_1_19_1","first-page":"309","volume-title":"Burkitt's lymphoma, a human cancer model. IARC Scientific Publication","author":"Lenoir G.","year":"1985"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/315669a0"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/317264a0"},{"key":"e_1_2_1_22_1","first-page":"276","article-title":"Establishment and characterization of an Epstein\u2010Barr virus (EBV) negative lymphoblastoid B cell line (BJA\u2010B) from an exceptional, EBV\u2010genome\u2010negative African Burkitt's lymphoma","volume":"22","author":"Menezes J.","year":"1975","journal-title":"Biomedicine"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.161.1.181"},{"key":"e_1_2_1_24_1","first-page":"835","article-title":"Establishment of lymphomatous cell lines from bone\u2010marrow samples from patients with Burkitt's lymphoma","volume":"73","author":"Philip I.","year":"1984","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910350404"},{"key":"e_1_2_1_26_1","doi-asserted-by":"crossref","first-page":"3111","DOI":"10.4049\/jimmunol.134.5.3111","article-title":"Comparison of the expression of IL2 receptors by human T and B cells: induction by the polyclonal mitogens, phorbol myristate acetate and anti\u2010\u03bc antibody","volume":"134","author":"Suzuki T.","year":"1985","journal-title":"J. Immunol."},{"key":"e_1_2_1_27_1","doi-asserted-by":"crossref","first-page":"678","DOI":"10.4049\/jimmunol.133.2.678","article-title":"Expression of C3d receptors during human B cell differentiation: immuno\u2010fluorescence analysis with the HB\u20105 monoclonal antibody","volume":"133","author":"Tedder T. F.","year":"1984","journal-title":"J. Immunol."},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V66.3.556.556"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.3.881"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910290609"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1963.7"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910380618","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910380618","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T23:03:03Z","timestamp":1697842983000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910380618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,12,15]]},"references-count":30,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1986,12,15]]}},"alternative-id":["10.1002\/ijc.2910380618"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910380618","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,12,15]]}}}