{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T21:40:55Z","timestamp":1698010855745},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":7034,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1987,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The murine monoclonal antibody (MAb) MA6 is selectively reactive against a large variety of human B lymphocytes including those in early stages of B\u2010cell differentiation such as committed progenitors of B lymphocytes, pre\u2010B lymphocytes, Burkitt lymphoma cells, and those at later stages of differentiation such as peripheral blood B lymphocytes and myeloma cells. The major antigen identified by this antibody on such B lymphocytes (BLCa) is a 55\u2010kDa glycoprotein or a group of similar glycoproteins, with the MA6\u2010reactive determinant localized on the carbohydrate moiety. On isoelectric focusing, this antigen exhibits a degree of charge microheterogeneity, migrating as a diffused band with an average isoelectric point at pH 5.7. BLCa was also identified by another murine MAb, MAS. The antigenic determinant recognized by this antibody is also localized on the carbohydrate moiety of the molecule, but, unlike the MA6\u2010reactive determinant, it is shared by other glycoproteins from different types of cells.<\/jats:p>","DOI":"10.1002\/ijc.2910390408","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T20:43:25Z","timestamp":1171917805000},"page":"452-458","source":"Crossref","is-referenced-by-count":8,"title":["Characterization of a human B\u2010lymphocyte carcinoma cross\u2010reacting antigen (BLCa) in B lymphocytes identified by two murine monoclonal antibodies"],"prefix":"10.1002","volume":"39","author":[{"given":"T. C.","family":"Yip","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. H.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. H.","family":"Ng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,18]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)91150-3"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.1985.36.3.329"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.12.4494"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj0890114"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910210504"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/227680a0"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/00313028509105505"},{"key":"e_1_2_1_9_1","volume-title":"Leucocyte Typing III","author":"McMichael A."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)81416-8"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00199769"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0968-0004(84)90139-7"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(86)90358-3"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applcations","volume":"76","author":"Towbin H.","year":"1979","journal-title":"Proc. nat. Acad. Sci. (Wash.)"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(85)90337-0"}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910390408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910390408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T23:01:53Z","timestamp":1697929313000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910390408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,4,15]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1987,4,15]]}},"alternative-id":["10.1002\/ijc.2910390408"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910390408","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,4,15]]}}}