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A total of 17 T\u2010cell cultures from 8 A\u2010T patients are compared with each other and with 5 T\u2010cell cultures from normal individuals. The large, cytogenetically abnormal t(14;14) and t(X;14) clones in 2 of the patients both occurred only in the CD8 + population of T lymphocytes. There was no difference in the rate of growth of A\u2010T T cells <jats:italic>in vitro<\/jats:italic> compared with those from normal individuals, although many of the original characteristics of the T cells were lost, including the cytogenetically abnormal clones seen in fresh A\u2010T lymphocytes.<\/jats:p>","DOI":"10.1002\/ijc.2910390604","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T20:43:02Z","timestamp":1171917782000},"page":"678-684","source":"Crossref","is-referenced-by-count":4,"title":["A comparison of fresh and cultured T lymphocytes from patients with ataxia telangiectasia using T\u2010cell subset markers and chromosome translocations"],"prefix":"10.1002","volume":"39","author":[{"given":"S. V.","family":"Butterworth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. M. 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