{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T15:36:46Z","timestamp":1789400206971,"version":"build-2803163510"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":6911,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1987,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>All records of ocular malignant melanoma notified to the Danish Cancer Registry between 1943 and 1982 were re\u2010coded, and 1,624 out of 1,650 cases were verified and included in this investigation. The annual number of incident cases increased from about 30 to 50, but the age\u2010standardized incidence rate remained stable at 0.75 per 100,000 in males and 0.60 In females. There was no predilection for one or the other eye in either sex. About 80% of the tumours were located in the choroid, 10% in the ciliary body and iris, 5% in the conjunctiva, and 5% in \u201cmultiple regions\u201d. The histopathology of the tumours was: epithelioid cell type in 12%, spindle\u2010cell type in 36%, and mixed\u2010cell type in 51%. The stable incidence rates of ocular malignant melanomas were in marked contrast to the 5\u2010to 6\u2010fold increase observed for cutaneous melanomas during the same time period. Possible differences in risk factors are discussed. Similarities and differences between the present data and results from other countries are highlighted.<\/jats:p>","DOI":"10.1002\/ijc.2910400206","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:10:17Z","timestamp":1171919417000},"page":"161-164","source":"Crossref","is-referenced-by-count":51,"title":["Trends in incidence of ocular malignant melanoma in Denmark 1943\u20131982"],"prefix":"10.1002","volume":"40","author":[{"given":"Anne","family":"\u00d8sterlind","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1983.tb04350.x"},{"key":"e_1_2_1_3_1","first-page":"9","article-title":"Ocular melanoma: a population based study","volume":"15","author":"Birdsell J. M.","year":"1980","journal-title":"Canad. J. Ophthalmol."},{"key":"e_1_2_1_4_1","series-title":"IARC, Scientific Publication 42","first-page":"671","volume-title":"Cancer incidence in five continents","author":"Doll R.","year":"1982"},{"key":"e_1_2_1_5_1","first-page":"775","article-title":"Risk factors for ocular melanoma: Western Canada Melanoma Study","volume":"74","author":"Gallagher R. P.","year":"1985","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_6_1","first-page":"143","article-title":"Cancer of the eye: a review of trends and differentials","volume":"31","author":"Hakulinen T.","year":"1978","journal-title":"World Hlth Slat. Q."},{"key":"e_1_2_1_7_1","first-page":"651","article-title":"A theory of the etiology and pathogenesis of human cutaneous malignant melanoma","volume":"71","author":"Holman C. D. J.","year":"1983","journal-title":"J. nat. Cancer Inst."},{"key":"e_1_2_1_8_1","first-page":"1","article-title":"Malignant melanomas of the uvea in Denmark 1943\u20131952. A clinical, histopathologidal and prognostic study","volume":"75","author":"Jensen O. A.","year":"1963","journal-title":"Acta ophthal. (kbh.)"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1093\/oxfordjournals.aje.a121519","article-title":"Histology, survivorship and related factors in the epidemiology of eye cancers","volume":"97","author":"Keller A. Z.","year":"1973","journal-title":"Amer. J. Epidemiol."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a036243"},{"key":"e_1_2_1_11_1","first-page":"1","article-title":"Uveal melanoma in Finland. An epidemiological, clinical, histological and prognostic study","volume":"133","author":"Raivio L.","year":"1977","journal-title":"Acta ophthal. (kbh.)"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/56.3.489"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113150"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113636"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1983.42"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1755-3768.1985.tb01577.x"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198509263131305"},{"key":"e_1_2_1_18_1","series-title":"IARC Scientific Publication 42","volume-title":"Cancer incidence in five continents","author":"Waterhouse J.","year":"1982"},{"key":"e_1_2_1_19_1","volume-title":"International Classification of Diseases for Oncology (iCD\u2010O.)","author":"WORLD HEALTH ORGANIZATION","year":"1976"},{"key":"e_1_2_1_20_1","volume-title":"Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death, 1955","author":"WORLD HEALTH ORGANIZATION.","year":"1957"},{"key":"e_1_2_1_21_1","first-page":"2483","article-title":"Evaluation of registration of cancer cases in Denmark in 1977","volume":"147","author":"\u00d8sterlind A.","year":"1985","journal-title":"Ugeskr. Laeger"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-82641-2_2"},{"key":"e_1_2_1_23_1","first-page":"361","article-title":"Second cancer following cutaneous melanoma and cancers of the brain, thyroid, connective tissue, bone, and eye in Denmark, 1943\u201380","volume":"68","author":"\u00d8sterlind A.","year":"1985","journal-title":"Nat. Cancer Inst. Monger."}],"container-title":["International Journal of Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fijc.2910400206","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ijc.2910400206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T14:30:49Z","timestamp":1697898649000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ijc.2910400206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,8,15]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1987,8,15]]}},"alternative-id":["10.1002\/ijc.2910400206"],"URL":"https:\/\/doi.org\/10.1002\/ijc.2910400206","archive":["Portico"],"relation":{},"ISSN":["0020-7136","1097-0215"],"issn-type":[{"value":"0020-7136","type":"print"},{"value":"1097-0215","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,8,15]]}}}