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All patients had negative PAP smears. Twenty\u2010six (28%) of the pregnant women and 12 (12.5%) of the non\u2010pregnant women were positive for HPV. HPV 16 accounted for 42% of all positive pregnant cases and only 25% of the positive non\u2010pregnant cases. Smears of pregnant patients contained more than 10 pg viral DNA in 45% of the cases against 20% in the non\u2010pregnant group. HPV 16 showed the most active replication in both groups. This study demonstrates an increased prevalence of HPV (preferentially of HPV 16) and a higher replication rate of viral DNA during pregnancy.<\/jats:p>","DOI":"10.1002\/ijc.2910400212","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:10:17Z","timestamp":1171919417000},"page":"198-201","source":"Crossref","is-referenced-by-count":188,"title":["Increased prevalence of human papillomaviruses in the lower genital tract of pregnant women"],"prefix":"10.1002","volume":"40","author":[{"given":"Achim","family":"Schneider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlies","family":"Hotz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutz","family":"Gissmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)90348-1"},{"key":"e_1_2_1_3_1","first-page":"17","volume-title":"Viral etiology of cervical cancer","author":"Brinton L. 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