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Even on the small island of Tsushima (710 km<jats:sup>2<\/jats:sup>; pop. 48,875; 123 villages), the positive rates of anti\u2010HTLV\u20101 antibody among the 58 villages studied varied from 2% to 50%, a fact that is probably associated with the historical events affecting the movement of the indigenous population of Tsushima Island. The positive rate of anti\u2010HTLV\u20101 antibody in males increased little with age; however, the female rate increased distinctly with age in moderate and high HTLV\u20101\u2010endemic villages where more than 15% of the inhabitants had positive anti\u2010HTLV\u20101 antibody. Analysis of anti\u2010HTLV\u20101 antibody positivity between spouses confirmed that HTLV\u20101 was more contagious from husband to wife than from wife to husband, which corresponded to the fact that the positive rate of anti\u2010HTLV\u20101 antibody in females older than 30 years was higher than that in males. Recently the rate of carrier children from HTLV\u20101 carrier mothers was estimated at around 20%. The recent annual incidence rates of ATL among 1,000 HTLV\u20101 carriers older than 40 years living in Tsushima Island was estimated at 2.2 in males, 0.8 in females.<\/jats:p>","DOI":"10.1002\/ijc.2910400605","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:05:39Z","timestamp":1171919139000},"page":"741-746","source":"Crossref","is-referenced-by-count":82,"title":["Epidemiological features of HTLV\u2010I carriers and incidence of ATL in an ATL\u2010endemic island: A report of the community\u2010based co\u2010operative study in Tsushima, Japan"],"prefix":"10.1002","volume":"40","author":[{"given":"Kazuo","family":"Tajima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sueo","family":"Kamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin\u2010Ichiro","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuko","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masazumi","family":"Nagatomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken\u2010Ichiro","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Ikeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910350304"},{"key":"e_1_2_1_3_1","first-page":"193","article-title":"A case of adult T\u2010Cell leukemia\/Lymphoma in a Korean\u2010Japanese man (nisei)","volume":"25","author":"Aozasa K.","year":"1984","journal-title":"Jap. 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