{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:12:56Z","timestamp":1790820776006,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":6789,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1987,12,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Okinawa prefecture is one of the endemic areas for adult T\u2010cell leukemia\/lymphoma (ATLL) in Japan. In this study, 2,013 serum specimens drawn serially over a period of 15 years (1968\u20131983) from 311 mother\/child pairs in Okinawa were tested for antibodies to human T\u2010cell leukemia virus type 1 (HTLV\u20101) by enzyme\u2010linked immunosorbent assay and by indirect Immunofluorescence. The prevalence rate of HTLV\u20101 antibodies was 20.9% (65 cases) in the mothers and 3.2% (10 cases) in the children. Of the 65 seropositive mothers, 10 (15.4%) had seropositive children. This study revealed a significant difference between the prevalence rates of HTLV\u20101 antibodies in mothers and children. In addition, children born to seropositive mothers had acquired their HTLV\u20101 antibodies by the age of 3 years, and were still seropositive at the age of 18 years. No initially seronegative child was found to have sero\u2010converted during the period investigated.<\/jats:p>","DOI":"10.1002\/ijc.2910400607","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T16:05:39Z","timestamp":1171901139000},"page":"755-757","source":"Crossref","is-referenced-by-count":84,"title":["Mother\u2010to\u2010child transmission of human T\u2010cell leukemia virus type I (HTLV\u20101): A fifteen\u2010year follow\u2010up study in Okinawa, Japan"],"prefix":"10.1002","volume":"40","author":[{"given":"Koichi","family":"Kusuhara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunro","family":"Sonoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Tokugawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junichiro","family":"Fukushige","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohji","family":"Ueda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,7,17]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"659","article-title":"Type\u2010I HTLV antibody of healthy adults in Okinawa and of Okinawans in Hawaii","volume":"27","author":"Araki K.","year":"1986","journal-title":"Jap. J. clin. Hemat."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.13.4895"},{"key":"e_1_2_1_4_1","first-page":"474","article-title":"Mother\u2010To\u2010Child transmission of human T\u2010Cell leukemia virus type\u2010I","volume":"76","author":"Hino S.","year":"1985","journal-title":"Gann"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.2910290606"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.10.6476"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1093\/oxfordjournals.aje.a114456","article-title":"Intrafamilial clustering of anti\u2010ATLA\u2010Positive persons","volume":"124","author":"Kajiyama W.","year":"1986","journal-title":"Amer. J. 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