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Shark liver oil (SLO) which was the main source of vitamin A in the standard diet, was deleted in one regimen and reduced to 25% in the other. The mice maintained on the former diet were given a high dose of DEN and those on the latter diet received a low dose. In both strains the deficient mice had a greater tumour incidence than those on standard diet with a marginal reduction in the latent period. At the low level of DEN there was shift in organotrophy, <jats:italic>i.e.<\/jats:italic> from liver in controls to lung in the vitamin\u2010A\u2010deficient mice of BALB\/c strain. With the higher dose, lung adenomas predominated in deficient as well as control groups in both the strains. Forestomach carcinomas appeared in deficient mice and not in the controls.<\/jats:p>","DOI":"10.1002\/ijc.2910400613","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:05:39Z","timestamp":1171919139000},"page":"784-787","source":"Crossref","is-referenced-by-count":5,"title":["Carcinogenicity of diethylnitrosamine in vitamin\u2010A\u2010deficient mice"],"prefix":"10.1002","volume":"40","author":[{"given":"Uma","family":"Santhanam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V. S.","family":"Lautha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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