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These were identified from the files of the nation\u2010wide clinical trial of the Danish Breast Cancer Cooperative Group and the Danish Cancer Registry. The control group was an age\u2010stratified random sample of 1,336 women from the general population. Data on risk factors were collected by self\u2010administered (mailed) questionnaires. The major findings included a trend (<jats:italic>p<\/jats:italic> = 0.001) toward decreasing risk with increasing age at menarche in pre\u2010menopausal women, trends toward increasing risk with continued menstrual cycles after the age of 50 in pre\u2010 and post\u2010menopausal women (<jats:italic>p<\/jats:italic>\u2010values of 0.01 and 0.002 respectively), and a trend (<jats:italic>p<\/jats:italic> = 0.002) toward increasing risk with increasing duration of non\u2010contraceptive sex hormone usage in post\u2010menopausal women. Information on brand names made it possible to examine types of hormones used, which showed an RR of 1.36 (95% CI 0.98\u20131.87) for sequential therapy with oestrogen and progestagen and RR = 2.31 (95% CI 1.37\u20133.88) for combined oestrogen\u2010androgen treatment. These results should be interpreted with caution, however, needing verification from other studies. No significant association was observed between breast cancer and self\u2010reported height and weight.<\/jats:p>","DOI":"10.1002\/ijc.2910420606","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T14:04:33Z","timestamp":1334066673000},"page":"832-838","source":"Crossref","is-referenced-by-count":149,"title":["Influence of non\u2010contraceptive exogenous and endogenous sex hormones on breast cancer risk in Denmark"],"prefix":"10.1002","volume":"42","author":[{"given":"Marianne","family":"Ewertz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,4,10]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech.41.2.94"},{"key":"e_1_2_1_3_1","volume-title":"The GLIM System: Release 3","author":"Baker R.J.","year":"1978"},{"key":"e_1_2_1_4_1","volume-title":"Comprehensive summaries of Uppsala Dissertations from the Faculty of Medicine","author":"Bergkvist L.","year":"1987"},{"key":"e_1_2_1_5_1","volume-title":"The analysis of case\u2010control studies","author":"Breslow N.E.","year":"1980"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1986.246"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810515)47:10<2517::AID-CNCR2820471035>3.0.CO;2-L"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/oxfordjournals.aje.a114632","article-title":"A prospective cohort study of postmenopausal hormone use and risk of breast cancer in US women","volume":"125","author":"Buring J.E.","year":"1987","journal-title":"Amer. 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