{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T08:25:38Z","timestamp":1768551938371,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,7,17]],"date-time":"2006-07-17T00:00:00Z","timestamp":1153094400000},"content-version":"vor","delay-in-days":6180,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intl Journal of Cancer"],"published-print":{"date-parts":[[1989,8,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Epidermal growth factor (EGF), dehydroepiandrosterone (DHA)\u2010sulphate and [Na<jats:sup>+<\/jats:sup>] and [K<jats:sup>+<\/jats:sup>] were assayed in 78 cyst fluids from patients with a palpable breast cyst. Epidermal growth factor was detected in all but 2 cysts, the mean value \u00b1 Sem being 506.2 \u00b1 39.3 ng\/ml, with a range of 0\u20101,599 ng\/ml. When the cyst fluids were sub\u2010divided according to their [Na<jats:sup>+<\/jats:sup>]:[K<jats:sup>+<\/jats:sup>] ratio, group A cyst fluids ([Na<jats:sup>+<\/jats:sup>]:[K<jats:sup>+<\/jats:sup>] &lt; 3) had a significantly higher (p &lt; 0.001) level of EGF than group B cyst fluids ([Na<jats:sup>+<\/jats:sup>]:[K<jats:sup>+<\/jats:sup>] &gt; 3). Furthermore, the relationship between EGF and [Na<jats:sup>+<\/jats:sup>] and [K<jats:sup>+<\/jats:sup>] and between EGF and DHA\u2010sulphate seemed to differ between the 2 cyst types and each cyst type was therefore analyzed separately.<\/jats:p>","DOI":"10.1002\/ijc.2910440207","type":"journal-article","created":{"date-parts":[[2007,2,19]],"date-time":"2007-02-19T21:40:04Z","timestamp":1171921204000},"page":"229-232","source":"Crossref","is-referenced-by-count":14,"title":["Quantification of epidermal growth factor in human breast cyst fluids: Correlation with dehydroepiandrosterone\u2010sulphate and electrolyte concentrations"],"prefix":"10.1002","volume":"44","author":[{"given":"K.","family":"Smith","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. R.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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